Archives of Clinical and Experimental Ophthalmology

Sickness rates of children living in regions with extreme environmental pollution resulted in our study evaluating effects of 30-day supplementation with two different food supplements containing nucleotides, amino acids and polypeptides or β-glucan. This study was based on published studies evaluating these effects on children with chronic respiratory problems transported to the region without environmental pollution and into the medical program complemented with climatotherapy, speleotherapy, higher motion activity, rehabilitation, and a special nutritional program. 

Upper eyelid height is primarily determined by the actions of the levator palpebrae superioris and Muller’s muscle. Muller’s muscle, a smooth muscle with a predominance of α-1D adrenergic receptors, contracts in response to sympathetic stimulation or adrenergic agonists. Compounds such as apraclonidine, a medication with mixed α and α-1 receptor agonist properties, have been shown to reverse ptosis caused by Horner’s syndrome and botulinum toxin-induced ptosis, and to help assess blepharoptosis preoperatively.

In the nightmare of the coronavirus pandemic that is spreading around the world, parents could take comfort in one thing - early reports that the virus mysteriously spares children, even though this often leads to critical illness in older people. An article published in the Journal “Pediatrics”, based on 2,143 young people in China, provides the most comprehensive evidence of the spread of the virus among children, and there is bad news and good news [1].

Phakic intraocular lenses have been available as an option for the treatment of refractive errors in eyes whose corneal surgical procedures such as photorefractive keratectomy (PRK), laser in situ keratomileusis (LASIK) or small incision lenticule extraction (Smile) are formally contraindicated or unacceptable [1-3]. 

Telemedicine is a sub-area of telematics in healthcare and refers to diagnostics and therapy bridging a spatial or temporal distance between doctor, therapist, pharmacist, and patient or between two doctors consulting each other by means of telecommunications.

In a recent attempt to elucidate the role of HIF1α in modulating the fate of T cells, we have demonstrated that the targeted deletion of HIF1α, specifically in T cells, enhances the inflammatory capabilities and memory phenotype of CD8+ T cells.

Non-alcoholic fatty liver disease (NAFLD) represents an escalating global health concern. Its prevalence varies significantly across different regions, in Asia it ranges from 30-32%, with notably higher prevalence in the Middle East. Europe reports a prevalence of 27-33%, while North America shows a range of 35-48%.

Despite a young age and limited exposure to nutritional challenges and other diseases, young children can develop liver disorders such as fatty liver, fibrosis, and liver cancer. The preliminary stages of these disorders are silent, and the patients come to the clinic at a late stage. During studies of pediatric liver cancer hepatoblastoma (HBL), our group found that a portion of our fresh HBL biobank is characterized by the development of Non-Alcoholic Fatty Liver Disease (NAFLD) including fatty liver, fibrosis, and increased proliferation. Our studies and other 

Asthma is classified as an inflammatory airway disorder. The triggering factors, such as aeroallergens, air pollutants, and viral infections, promote asthma symptoms . Despite the progress made in the prevention and management of the disease, unfortunately, the number of morbidities is increasing every year.

In 2021, older adults were making up about 13.5% of the global population and projections indicated that by 2030, one in six people would be aged 60 years or more. Aging is associated with a progressive decline in exercise capacity, along with changes in physical function and walking ability, which can influence the performance of daily activities and the preservation of personal independence.

Achondroplasia is the most common form of genetically inherited dwarfism. Affected individuals are mainly characterized by severely shortened arms and legs and a large head. In 1878, the term achondrodysplasia was coined by the French physician Joseph Marie Jules Parrot. The term achondroplasia is purely historical and does not explain the cause or manifestations of this disorder.

Purpose: Nd:YAG laser capsulotomy is an effective treatment for posterior capsule opacification (PCO) but may be associated with postoperative increases in intraocular pressure (IOP), particularly in high-risk patients. This study evaluated the incidence of IOP elevation following Nd:YAG laser capsulotomy, the management strategies used, and clinical outcomes at a tertiary eye hospital in Nigeria. Methods: This retrospective cohort study included 162 patients aged 40–80 years who underwent Nd:YAG laser capsulotomy for PCO and completed at least one year of follow-up. Data on demographic characteristics, IOP measurements, visual acuity outcomes, and post-procedure management were extracted from medical records. Changes in IOP and visual acuity before and after the procedure were analyzed, and outcomes were compared between patients with and without pre-existing glaucoma.

Neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are increasingly prevalent in children globally, including Cameroon. Emerging evidence suggests that early-life exposure to environmental neurotoxins, particularly mycotoxins, may disrupt brain development and contribute to these disorders.