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Journal of Rehabilitation Research and Practice
ISSN: 2694-0388
Volume 7, Issue 1, p1-51
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
Analysis of SSR, NCS/EMG, and HRV testing in chronic pain programs: clinical relevance and cost effectiveness
Background: Chronic pain often includes unrecognized neuropathic and autonomic components that are not fully captured by routine clinical examination, potentially delaying accurate diagnosis and prolonging opioid therapy—particularly concerning in high-risk populations identified by elevated Narcotic Risk Index (NARX) scores.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p1-9 | DOI: 10.46439/rehabilitation.7.043
Artificial intelligence in rehabilitation
Artificial intelligence (AI) is used in various fields, including rehabilitation. The main goal of using this technology is to enhance the performance of individuals with different disorders. Additionally, AI is utilized to improve diagnostic procedures and monitor the progress of patients. The main question that arises is how AI impacts the field of rehabilitation and what are the advantages and disadvantages of using this technology in rehabilitation.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p10-13 | DOI: 10.46439/rehabilitation.7.044
The evolving paradigm of rehabilitation: personalization, equity, and integration
The collection of articles in this issue of the Journal of Rehabilitation Research and Practice presents a compelling and thoughtfully curated snapshot of the contemporary rehabilitation landscape. This journal continues to demonstrate its commitment to publishing high-impact, socially relevant research that pushes the boundaries of the field.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p14-15 | DOI: 10.46439/rehabilitation.7.045
Heart rate variability and ultra-processed food addiction screening as predictive biomarkers in high-risk pain management: a retrospective cohort analysis
Background: The opioid epidemic highlights the need for objective biomarkers that identify high-risk chronic pain patients before overdose events occur. Existing prescription drug monitoring programs such as the NARX score are primarily reactive, underscoring the potential value of physiologic and behavioral risk markers.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p16-21 | DOI: 10.46439/rehabilitation.7.046
Physical activity, sedentary lifestyle, and muscle wasting in hemodialysis patients: a structured narrative review
Background: Hemodialysis (HD) patients experience severe physical deconditioning due to extremely low physical activity, prolonged sedentary behavior, and progressive muscle wasting. These changes accelerate frailty, impair functional independence, reduce quality of life (QoL), and increase hospitalization and mortality risks. Sarcopenia is now recognized as a key predictor of poor outcomes in this population.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p22-32 | DOI: 10.46439/rehabilitation.7.047
Evaluation of the anti-inflammatory and wound-healing potentials of Nigella sativa extract in dermal injury models
Skin repair depends on balanced inflammation, oxidative control, and growth-factor signaling. Disruption of these events delays healing and leads to chronic wounds. Nigella sativa (black seed) contains bioactive compounds such as thymoquinone with anti-inflammatory and antioxidant activity, but its integrated effect on dermal repair remains unclear.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p33-38 | DOI: 10.46439/rehabilitation.7.048
Health and safety has saved lives at work – It has not prevented disability
Health and Safety (H&S) regulation has been one of the most successful public health interventions of the twentieth century, dramatically reducing fatal workplace injuries in high-income countries. However, while H&S has been effective in preventing death and acute injury, it has been far less effective in addressing the dominant occupational health problem of the contemporary workforce: work-related disability.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p39-42 | DOI: 10.46439/rehabilitation.7.049
Multimodal physiotherapy in the management of plantar fasciitis: A narrative systematic review
Background: Plantar Fasciitis (PF) is one of the most common causes of heel pain, affecting a significant proportion of the adult population. Despite the availability of various treatment modalities, there remains variability in clinical practice and outcomes.
J Rehabil Res Pract, 2026, Volume 7, Issue 1, p43-51 | DOI: 10.46439/rehabilitation.7.050
New Frontiers in the Rehabilitation of Neurological Damage
Epidemiologic data show a high incidence of central nervous system (CNS) disease, which therefore is a prominent healthcare issue. Adults and the elderly are most commonly affected, with heavy repercussions on society and caregivers. The outcome of CNS disease, whether the etiology is vascular, degenerative or traumatic, is often significant disability or death. Motor, language and cognitive deficits are most prevalent, but vision is also frequently affected, in the form of visual field defects or oculomotor and binocular disorders. In the present paper, we discuss peripheral and central visual field defects.
Ocular surface squamous neoplasia treated with topical chemotherapy
A man in his 90s presented to clinic with a conjunctival lesion on the right eye noticed two months prior. The patient denied pain but endorsed worsening blurry vision. The patient’s past medical history was significant for skin cancer on the right ear removed 3 years ago, and a history of ocular surface lesion removal on one eye approximately 20 years ago that was negative for any neoplasia. Slit lamp photograph revealed a gelatinous and opalescent lesion suspicious for ocular surface squamous neoplasia (OSSN) and the high-resolution optical coherence tomography (HROCT) cut (arrow)
Modulating the immunotolerant tumor microenvironment to enhance irreversible electroporation ablation therapy
Over the years, several ablation techniques, such as radiofrequency ablation (RFA), microwave ablation, and cryoablation, have been developed and implemented in the treatment of different cancers. Of these ablation technologies, RFA is the most widely used. RFA is a form of thermal ablation that relies on radio waves to produce an electrical current at the tip of an inserted electrode, thus allowing for heat production at the site of the tumor.
Goals for pediatric inpatient pain management: Best care everywhere
Acute pain is defined as an unpleasant sensory and emotional experience associated with, or resembling actual or potential tissue damage as a result of a surgical procedure, physical trauma, or as a consequence of a medical condition [1]. The prevalence of moderate-severe pain, defined as pain which significantly interferes with daily living activities, ranges between 27% and 66% in hospitalized pediatric patients and remains inconsistent even in those institutions with excellent resources and good reputations [2,3].
Upregulation of long noncoding RNA growth arrest-specific 5 mediates pro-inflammatory mechanisms of diabetic wound healing impairment
Unresolved inflammatory processes contribute to impaired healing in diabetic wounds, with increasing evidence implicating persistent pro-inflammatory macrophage polarization as a driver of chronic inflammation and delayed wound closure. Previous investigations aimed to uncover the role of regulatory RNAs in macrophage polarization and to understand how aberrant expression patterns contribute to wound healing impairment, with the goal of identifying novel therapeutic targets for promoting normal wound healing progression. In the Journal of Investigative Dermatology, Hu et al. reveal a role of the tumor suppressor, long noncoding RNA (lncRNA) Growth Arrest-Specific 5 (GAS5), in regulating macrophage polarization.
Improving cardiac rehabilitation referral rates in patients with coronary heart disease from diverse communities using an electronic order system
Cardiac Rehabilitation (CR) is a medically supervised preventative cardiovascular program that involves a multi-disciplinary approach including physician-prescribed exercises, cardiac risk factor modification (education, counseling, and behavioral intervention), psycho-social assessment, outcomes assessment, and individual treatment plans [1,2].
The tumor dose sensitivity matrix and stem cells in head and neck cancer
Radiation therapy (RT) is one of the pillars of locally advanced head and neck cancer (HNSCC) treatment in combination with cisplatin or epidermal growth factor receptor inhibitors. Despite a very high local tumor control rate, approximately 50% of patients with locally advanced disease will develop a recurrence.
Occurrence of cervical spine arthritis highly responsive to adalimumab in a patient with psoriatic peripheral arthritis and longstanding remission while on etanercept therapy
Cervical spine involvement frequently occurs in patients with Psoriatic Arthritis (PsA) even in absence of sacroiliitis. Long disease duration, high disease activity in the first five years and presence of peripheral involvement are all predictors of this peculiar articular involvement.
An atypical case of compressive optic neuropathy and cranial nerve 6th palsy caused by a cholesterol granuloma
In this case report we present an unusual case of orbital cholesterol granuloma associated with compressive optic neuropathy and cranial nerve 6th palsy. Cholesterol granuloma results from a foreign body response to the presence of crystallized cholesterol. Cholesterol granuloma affecting the orbit are a rare presentation as they typically occur in the petrous apex of the temporal bone.
Physical Therapy in Mental Health?
At the beginning there was an international network of physical therapists working in the field of psychiatry and mental health with the origin at Leuven University (Belgium) from in 2006. The International Organization of Physical Therapy in Mental Health (IOPTMH) was accepted as a World Confederation for Physical Therapy (WCPT) subgroup at the 17th General Meeting, in 2011 and reconfirmed in 2015 and 2019, including 21 member countries, Australia, Austria, Belgium, Colombia, Denmark, Estonia, Finland, Greece, Iceland, Japan, Latvia, Mexico, The Netherlands, Norway, Poland, Spain, South Africa, Sweden, Switzerland, Turkey, UK, but within IOPTMH, there is a network of individual physical therapists, representing 59 nations from 6 continents.
Physiotherapy in Mental Health Facing the Covid-19 Pandemic
According to the International Organization of Physical Therapy in Mental Health (IOPTMH), physiotherapy in mental health is a recognized specialty of physical therapy, with a subgroup representing physiotherapists from around the world before the World Confederation of Physical Therapy (WCPT). It is implemented in different settings, in health, psychiatry and psychosomatic medicine.
Commentary on: Some aspects of rehabilitation of the disabled elderly at the present stage
According to the United Nations, to date the number and proportion of elderly grows much faster than in other age groups. The increase in the total number of elderly persons in the population of the globe makes the actual problems of social and economic consequences of population ageing. The issue of ensuring the quality of life of older people becomes an important and urgent task of the state.
Parkinson’s disease: cell therapy vs. gene therapy
Parkinson’s disease (PD) is the second most common neurodegenerative disease, manifesting as a characteristic movement disorder with a number of additional non-motor features. The pathological hallmark of PD is the presence of intra-neuronal aggregates of a-synuclein (Lewy bodies). The movement disorder of PD occurs largely due to loss of dopaminergic neurons of the substantia nigra, resulting in striatal dopamine depletion.
Effect of educational level on Alzheimer's disease-related biomarkers: Commentary
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive impairments that might be accompanied by declines in activities of daily living, neuropsychiatric disorders and a loss of motor function [1,2]. At present, the prevalence of dementia of Alzheimer’s type (DAT) is approximately 4% among elderly people [3]. With the increase in the aging the population, the number of individuals with DAT is still increasing.
Impact of hemisphere localization and the frequency of physical and occupational therapy sessions on functional independence of stroke patients in inpatient rehabilitation
Stroke is the 5th leading cause of death and the leading cause of long-term disability in the United States. Every 40 seconds, someone in the United States sustains a stroke, resulting in approximately 133,000 deaths per year. Stroke related deaths accounted for 11.8% of total deaths in 2015, making stroke the second leading cause of death worldwide, second only to heart disease
Pulmonary rehabilitation in candidates for bronchoscopic lung volume reduction
Bronchoscopic lung volume reduction (BLVR) may be considered in Chronic Obstructive Pulmonary Disease (COPD) patients with advance emphysema who are symptomatic and have refractory hyperinflation despite optimal medical therapy and pulmonary rehabilitation.
Efbemalenograstim alfa, a long-acting granulocyte colony-stimulating factor, a novel dimeric G-CSF Fc fusion protein for reducing the risk of febrile neutropenia following chemotherapy
Chemotherapy?induced neutropenia (CIN) can cause life-threatening complications such as febrile neutropenia (FN) or other infections. Patients who develop FN often require prolonged hospitalizations and treatment with broad-spectrum antibiotics.
Artificial intelligence and the future of transfusion medicine
Transfusion Medicine (TM) is a relatively young medical discipline supporting a large number of medical specialties on an almost daily basis. In de routine of TM large amounts of data are collected and processed in a standardized way and depending on the economy of scale practiced. Blood and its components are not without risk when transfused.
Renal rehabilitation: Recommendations of exercise therapies in patients with kidney diseases
Renal rehabilitation is a process to conduct treatments for the patients suffering from kidney disease and support to help them for their smooth achievement of social rehabilitation. Patients with dialysis-dependent kidney failure carry some additional burden of co-morbidity, such as, diabetes mellitus, hypertension, cardiovascular disease, infections, and many other. Approximately 10% of the world population is affected by chronic kidney disease and the incidence of dialysis is quite high.
Commentary on “Ultrasmall polyvinylpyrrolidone-modified iridium nanoparticles with antioxidant and anti-inflammatory activity for acute pancreatitis alleviation”
Acute pancreatitis (AP) can lead to severe body damage, including a systemic inflammatory response and multiorgan failure, and current therapies rely heavily on symptomatic treatment and supportive care, with a lack of targeted therapeutic strategies for specific pathologic processes.