Journal of Allergy and Infectious Diseases

2024

Volume 5, Issue 1, p1-68

Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.

Commentary Open Access

Selective antibody deficiency syndrome, response to vaccines, diagnosis, and treatment

Alonso-Bello César Daniel, Hernández-Nieto Leticia, Moncayo-Coello Carol Vivian, Graciela Hernández-Silva, Castillo-Narváez Gloria, Mellado-Ábrego Jaime, Ballesteros-González Diego, Ríos-Núñez Elida Berenice, Rico-Rojas David, Rojo-Gutiérrez María Isabel

Selective antibody deficiency syndrome (SAD), is a primary immunodeficiency in which immunoglobulin levels remain normal, but there is a reduced response to polysaccharide antigens after vaccination. SAD is recognized by the International Union of Immunology Societies as a primary immunodeficiency of unknown genetic cause. Patients with SAD are highly susceptible to severe respiratory tract infections with encapsulated bacteria.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p1-5 | DOI: 10.46439/allergy.5.039

Commentary Open Access

COVID-19 in the post-vaccination era: Who is at risk of severe disease?

Alonso-Bello César Daniel, Pérez-Barragán Edgar, Moncayo-Coello Carol Vivian, Rojo-Gutiérrez María Isabel

Vaccination against SARS-CoV-2 began in December 2020 and with this strategy, the course of the pandemic would be modified. BNT162b2 (Pfizer–BioNTech), mRNA-1273 (Moderna), and ChAdOx1 nCoV-19 (Oxford–AstraZeneca) were the main vaccines that demonstrated a reduction in hospitalization and death from SARS-CoV-2 in clinical trials. Post-vaccination infection by COVID-19 is called breakthrough infection.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p6-8 | DOI: 10.46439/allergy.5.040

Research Article Open Access

Dominated respiratory infections which exacerbate asthma in asthmatic children

Ali Mirhosseini, Hamid Ahanchian, Samira Basharkhah, Amir Hashem Asnaashari, Faezeh Sabet, Fatemeh Sadat Mohammadi, S.A Rahim Rezaee

Asthma is classified as an inflammatory airway disorder. The triggering factors, such as aeroallergens, air pollutants, and viral infections, promote asthma symptoms . Despite the progress made in the prevention and management of the disease, unfortunately, the number of morbidities is increasing every year.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p9-16 | DOI: 10.46439/allergy.5.041

Commentary Open Access

Mitochondrial disease patients and rotavirus infection complications

Savannah Battleson, Anna Betler, Hayden Divers, Jack Kloecker, Iradukunda Esperance, Nicholas Farrell, Molly Sawyer, Azhar Rahama, Ojus Dalvi, Gary Vanderlaan

Rotavirus (RV) is an agent of gastroenteritis and, to a lesser extent, neurological manifestations including seizures and epilepsy. Before the development of effective vaccines, rotavirus was among the leading global drivers of life-threatening diarrhea in neonates and children less than five years of age.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p17-28 | DOI: 10.46439/allergy.5.042

Commentary Open Access

Effects of helminth co-infections on COVID-19 outcome

Leonor Chacín-Bonilla

Helminths exert systemic immunomodulatory effects characterized by a deviation to a Th2 pattern cytokines. The potential detrimental influence of preexisting helminths infections on COVID-19 by the Th2-like cytokine response is a concern in helminths endemic areas. However, there is also the assumption that preexisting helminth infections may be beneficial by reducing the uncontrolled Th1 pro-inflammatory cytokine response and disease severity.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p29-34 | DOI: 10.46439/allergy.5.043

Research Article Open Access

Chemical characterization of red imported fire ants with colony development

Jian Chen

The red imported fire ant, Solenopsis invicta Buren, poses a significant threat to public health due to its venomous stings. While the chemistry of fire ants has been well investigated, most studies have focused on ants from mature colonies. The dynamic changes in chemical compositions during colony development have been less explored. In this study, we established S. invicta colonies using newly collected queens from the field and then tracked the chemistry of workers as the colonies developed. Our findings reveal that the chemistry of fire ant workers undergoes significant changes with the development of the colonies. However, the change in chemical diversity was not necessarily in the same direction for all individual glands.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p35-43 | DOI: 10.46439/allergy.5.044

Research Article Open Access

Impact of vaccination and testing levels on the COVID-19 waves

Igor Nesteruk

The first studies of the effectiveness of SARS-CoV-2 testing appeared in 2020 immediately after the pandemic outbreak. In 2021, with the advent of a sufficient number of vaccinated people, it became possible to study the impact of vaccination levels on the COVID-19 pandemic dynamics. Constant changes in its dynamics caused by changes in quarantine conditions and algorithms for testing and vaccination, the emergence of new strains require updating and rethinking the results of previous studies.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p44-55 | DOI: 10.46439/allergy.5.045

Research Article Open Access

Load-and-go molecular diagnostics for human papilloma virus detection

Minal Dakhave, Amrita Khaire, Shruti Gadekar, Kamini Patil

The present study describes analytical and clinical performance of the HPV 16 & 18 assay for the detection of HPV specific DNA with near point-of-care utility. A room temperature compatible real time PCR test was developed for detection and discrimination of HPV 16/18 in a single tube. The test was integrated and validated on Compact series automated platform for analytical performance (sensitivity, specificity, accuracy).

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p56-61 | DOI: 10.46439/allergy.5.046

Review Article Open Access

Applications of impulse oscillometry in the diagnosis and monitoring of preschool asthma

Alberto Vidal

Impulse oscillometry is a lung function test that has become more widely used over the past 30 years. It is particularly useful in patients who have difficulty performing forced respiratory maneuvers, such as preschool children, who have shorter expiration times, less strength to inhale, less coordination and shorter attention spans than older children or adults.

J Allergy Infect Dis, 2024, Volume 5, Issue 1, p62-68 | DOI: 10.46439/allergy.5.046

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