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The Neuroscience Chronicles
ISSN: 2767-3405
Volume 2, Issue 1, p1-24
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
Effect of educational level on Alzheimer's disease-related biomarkers: Commentary
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive impairments that might be accompanied by declines in activities of daily living, neuropsychiatric disorders and a loss of motor function [1,2]. At present, the prevalence of dementia of Alzheimer’s type (DAT) is approximately 4% among elderly people [3]. With the increase in the aging the population, the number of individuals with DAT is still increasing.
Neurosci Chron, 2021, Volume 2, Issue 1, p1-3 | DOI: 10.46439/Neuroscience.2.006Inhibition of 11β-HSD1, a key enzyme in the stress management, improves cognition by RL-118 drug treatment
In recent years, stress and stress-coping mechanisms constitute a growing public healthcare issue concerning modern society. Experiencing stress engenders a great complex mechanism named stress response, which consists of a rapid release of catecholamines by the sympathetic nervous system, followed by a slower response in which hormones, mainly glucocorticoids (GCs), are synthesized and released to the bloodstream.
Neurosci Chron, 2021, Volume 2, Issue 1, p4-8 | DOI: 10.46439/Neuroscience.2.007A commentary on telehealth and telemedicine in the COVID-19 era: A world of opportunities for the neurosurgeon
The COVID-19 pandemic has produced unprecedented conditions and difficulties for the global delivery of healthcare services. In this situation, all the healthcare employees, including neurosurgeons are facing many complexities. Telemedicine has decreased the spread of infection between neurosurgeons and patients.
Neurosci Chron, 2021, Volume 2, Issue 1, p9-10 | DOI: 10.46439/Neuroscience.2.008Propriospinal neurons involved in coordination of the bladder and urethra
Storage and periodic elimination of urine requires coordinated activity of the bladder and the urethral outlet. This coordination is provided by a complex neural control system in the brain and spinal cord. Experimental studies in animals show that urine storage is modulated by reflex mechanisms located in the sacral spinal cord, whereas urine release is mediated by pontine micturition center in the brainstem.
Neurosci Chron, 2021, Volume 2, Issue 1, p11-18 | DOI: 10.46439/Neuroscience.2.009Investigating putative psychoactive compounds using planarians as an animal model using the environmental place conditioning protocol
There is a seemingly endless list of compounds used by humans that may have psychoactive reinforcing properties underlying their repeated use; many have never been adequately studied. In a 2019 paper, the potential reinforcing properties of cotinine, a major nicotine metabolite, were investigated for the first time. To pursue this line of inquiry, cotinine was assessed using the planarian as an animal model in environmental place conditioning (EPC) also known as conditioned place preference (CPP).
Neurosci Chron, 2021, Volume 2, Issue 1, p19-24 | DOI: 10.46439/Neuroscience.2.010COVID-19 and burnout of physicians redeployed to emergency care
The COVID-19 pandemic of 2020-2023 significantly affected emergency medical care. Physicians who regularly saw their patients by appointment were redeployed to emergency care, increasing their reported burnout. Understanding how the burnout of specialists increased from this redeployment during COVID-19 is relevant to finding ways to reduce redeployment burnout in these appointment-based physicians when preparing for future pandemics.
Planned procedures and covid-19 pandemic: Does recovery plan, a matter of urgency?
The COVID-19 pandemic brought many challenges to each sector of life. The most affected are the health in general and elective services in specific. The postponement of planned surgical procedures is one of the elective services that not only increased the waiting time in the short-term but will strain the healthcare services in the long-run
Healthcare professionals’ awareness and knowledge of COVID-19 and radiation safety
Background: lack of knowledge and awareness of COVID-19 and radiation safety among healthcare professionals will adversely affect their health and the patients’ safety due to unnecessary radiation exposure and rapid spread of COVID-19. The purpose of this study is to evaluate the knowledge and the awareness of both domains; COVID-19 and radiation awareness in one survey study.
Anesthetic considerations for previously COVID-19 positive patients: design and rapid implementation of a perioperative surgical home (PSH) program
The COVID-19 pandemic presents unprecedented challenges for anesthesia professionals and their surgical patients. Beyond managing infection risk, positive COVID-19 surgical patients add additional challenges to their perioperative care, where its perioperative risk are superimposed onto an already baseline anesthesia risk in real-time with an unknown and unpredictable fashion.
COVID-19 and the Liver: Uncovering the Hidden Culprit behind Liver Injury
The effects of COVID-19 have been of increasing interest in all fields of medicine after the pandemic, especially considering the important impact and incidence of patients infected with coronavirus. Numerous studies have reported the vast clinical implications related to permanent organ and tissue damage after infection and long COVID.
Auditory system and COVID-19
The COVID-19 pandemic that emerged in 2020 may affect the peripheral and central auditory system. According to studies in the literature, symptoms affecting the vestibulocochlear system such as sudden hearing loss, tinnitus, and vestibular neuritis are seen in individuals with COVID -19.
A case of trigeminal neuralgia after COVID-19
The trigeminal nerve is one of twelve pairs of cranial nerves that attach to the brain. The name “trigeminal” literally means three twins and refers to the fact that the fifth cranial nerve has three major divisions: the ophthalmic (V1), the maxillary (V2), and the mandibular (V3) [1]. The trigeminal nerve is the major sensory nerve of the face and is the nerve of the first branchial arch.
Physiotherapy in Mental Health Facing the Covid-19 Pandemic
According to the International Organization of Physical Therapy in Mental Health (IOPTMH), physiotherapy in mental health is a recognized specialty of physical therapy, with a subgroup representing physiotherapists from around the world before the World Confederation of Physical Therapy (WCPT). It is implemented in different settings, in health, psychiatry and psychosomatic medicine.
Association of COVID-19 coronavirus and Kawasaki syndrome like features in 1-5 years old children
In the nightmare of the coronavirus pandemic that is spreading around the world, parents could take comfort in one thing - early reports that the virus mysteriously spares children, even though this often leads to critical illness in older people. An article published in the Journal “Pediatrics”, based on 2,143 young people in China, provides the most comprehensive evidence of the spread of the virus among children, and there is bad news and good news [1].
Effect of educational level on Alzheimer's disease-related biomarkers: Commentary
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive impairments that might be accompanied by declines in activities of daily living, neuropsychiatric disorders and a loss of motor function [1,2]. At present, the prevalence of dementia of Alzheimer’s type (DAT) is approximately 4% among elderly people [3]. With the increase in the aging the population, the number of individuals with DAT is still increasing.
Inhibition of 11β-HSD1, a key enzyme in the stress management, improves cognition by RL-118 drug treatment
In recent years, stress and stress-coping mechanisms constitute a growing public healthcare issue concerning modern society. Experiencing stress engenders a great complex mechanism named stress response, which consists of a rapid release of catecholamines by the sympathetic nervous system, followed by a slower response in which hormones, mainly glucocorticoids (GCs), are synthesized and released to the bloodstream.
A commentary on telehealth and telemedicine in the COVID-19 era: A world of opportunities for the neurosurgeon
The COVID-19 pandemic has produced unprecedented conditions and difficulties for the global delivery of healthcare services. In this situation, all the healthcare employees, including neurosurgeons are facing many complexities. Telemedicine has decreased the spread of infection between neurosurgeons and patients.
Propriospinal neurons involved in coordination of the bladder and urethra
Storage and periodic elimination of urine requires coordinated activity of the bladder and the urethral outlet. This coordination is provided by a complex neural control system in the brain and spinal cord. Experimental studies in animals show that urine storage is modulated by reflex mechanisms located in the sacral spinal cord, whereas urine release is mediated by pontine micturition center in the brainstem.
Investigating putative psychoactive compounds using planarians as an animal model using the environmental place conditioning protocol
There is a seemingly endless list of compounds used by humans that may have psychoactive reinforcing properties underlying their repeated use; many have never been adequately studied. In a 2019 paper, the potential reinforcing properties of cotinine, a major nicotine metabolite, were investigated for the first time. To pursue this line of inquiry, cotinine was assessed using the planarian as an animal model in environmental place conditioning (EPC) also known as conditioned place preference (CPP).
Mass food challenges in a vacant COVID-19 step-down facility: reflections on the management of anaphylaxis
A popular western misconception dating back to at least the time of President John F Kennedy is that one of the Chinese characters in the word “crisis” means opportunity. The manuscript
“Management of anaphylaxis in children undergoing oral food challenges in an adapted COVID-19 field hospital” [1] detailed a highly successful attempt to not only mitigate the effects of the crisis for
elective care brought by the COVID-19 pandemic but to seek to maximize the opportunity by better utilization and redeployment of staff allowing the team to reduce pre-pandemic waiting lists by 57%.
Vaccination, politics and COVID-19 impacts: update
In an earlier manuscript, the author found a strong relationship between political views, vaccination levels and COVID-19 death rates. This study revealed that in U.S. counties where large proportions of voters cast their ballot for Donald Trump in the 2020 presidential election, vaccination levels were lower and COVID-19 death rates were higher. This update explores this relationship six months later when more recent data are available. The updated analysis found that with the passage of time, the relationship between political views, vaccination levels and COVID-19 death rates became even stronger.
Spinal cord infarction associated with severe acute respiratory syndrome coronavirus 2: A case series of diagnostic challenges and postacute sequelae of COVID-19
Spinal cord infarction is extremely uncommon among vascular events, accounting for only 0.3-1% of all strokes and 5-8% of acute myelopathies. While deep vein thrombosis, pulmonary embolism, and stroke are commonly observed complications of COVID-19, spinal cord infarction is relatively rare.
Pediatric telemedicine and abdominal pain in children
Telemedicine is a sub-area of telematics in healthcare and refers to diagnostics and therapy bridging a spatial or temporal distance between doctor, therapist, pharmacist, and patient or between two doctors consulting each other by means of telecommunications.
Exploring Immune Cell Profiles and NLRP3 Gene Expression as Potential Diagnostic Markers in COVID-19 Patients: A Commentary
The COVID-19 pandemic caused by the SARS-CoV-2 virus continues to impact populations worldwide, emphasizing the need for improved diagnostic and treatment strategies. Understanding the immune response and identifying early diagnostic markers are crucial in this endeavor. In this comprehensive commentary, we delve into a recent study that investigated the immune cell profiles and NLRP3 gene expression as potential diagnostic markers in COVID-19 patients.
Short comment on COVID-19 pandemic in Mongolia
Mongolia is located between Russia to the north and China to the south, where it neighbors the Inner Mongolia Autonomous Region. The total population in Mongolia is about 3.3 million and nearly half of the people live in the capital, Ulaanbaatar, and in other provincial centers.