Loading
Archives of Autoimmune Diseases
ISSN: 2767-3340
Volume 4, Issue 1, p1-9
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
COVID-19 and the Liver: Uncovering the Hidden Culprit behind Liver Injury
The effects of COVID-19 have been of increasing interest in all fields of medicine after the pandemic, especially considering the important impact and incidence of patients infected with coronavirus. Numerous studies have reported the vast clinical implications related to permanent organ and tissue damage after infection and long COVID.
Arch Autoimmune Dis, 2023, Volume 4, Issue 1, p1-3 | DOI: 10.46439/autoimmune.4.014
Positive-DAT and autoimmune manifestations in patients with JAK2V617F mutation
Myeloproliferative neoplasms (MPN) are occasionally associated with autoimmune manifestations. The prevalence of positive direct antiglobulin test (DAT) in patients with JAK2V617F mutation is not yet known.
Arch Autoimmune Dis, 2023, Volume 4, Issue 1, p4-9 | DOI: 10.46439/autoimmune.4.015
Ocular surface squamous neoplasia treated with topical chemotherapy
A man in his 90s presented to clinic with a conjunctival lesion on the right eye noticed two months prior. The patient denied pain but endorsed worsening blurry vision. The patient’s past medical history was significant for skin cancer on the right ear removed 3 years ago, and a history of ocular surface lesion removal on one eye approximately 20 years ago that was negative for any neoplasia. Slit lamp photograph revealed a gelatinous and opalescent lesion suspicious for ocular surface squamous neoplasia (OSSN) and the high-resolution optical coherence tomography (HROCT) cut (arrow)
Etrasimod: A promising therapeutic candidate against Multiple Sclerosis
Multiple sclerosis (MS) is central nervous system (CNS) based disease. It is a chronic inflammatory demyelinating disease [1]. The main causes for MS are genetic and environmental factors. It is a disease of young people (median age of onset is around 28 years) but is lifetime and is often disabling; 50% of patients need a cane to walk 15 years after disease onset; and Worldwide more than 2.5 Million persons are affected.
COVID-19 and burnout of physicians redeployed to emergency care
The COVID-19 pandemic of 2020-2023 significantly affected emergency medical care. Physicians who regularly saw their patients by appointment were redeployed to emergency care, increasing their reported burnout. Understanding how the burnout of specialists increased from this redeployment during COVID-19 is relevant to finding ways to reduce redeployment burnout in these appointment-based physicians when preparing for future pandemics.
Planned procedures and covid-19 pandemic: Does recovery plan, a matter of urgency?
The COVID-19 pandemic brought many challenges to each sector of life. The most affected are the health in general and elective services in specific. The postponement of planned surgical procedures is one of the elective services that not only increased the waiting time in the short-term but will strain the healthcare services in the long-run
Healthcare professionals’ awareness and knowledge of COVID-19 and radiation safety
Background: lack of knowledge and awareness of COVID-19 and radiation safety among healthcare professionals will adversely affect their health and the patients’ safety due to unnecessary radiation exposure and rapid spread of COVID-19. The purpose of this study is to evaluate the knowledge and the awareness of both domains; COVID-19 and radiation awareness in one survey study.
Anesthetic considerations for previously COVID-19 positive patients: design and rapid implementation of a perioperative surgical home (PSH) program
The COVID-19 pandemic presents unprecedented challenges for anesthesia professionals and their surgical patients. Beyond managing infection risk, positive COVID-19 surgical patients add additional challenges to their perioperative care, where its perioperative risk are superimposed onto an already baseline anesthesia risk in real-time with an unknown and unpredictable fashion.
Stromal cells set the myeloma bone marrow on fire
Multiple myeloma is a blood-borne cancer with its cell-of-origin in plasma cells or progenitors of plasma cells. In contrast to the extensively studied biology of myeloma cells, the bone marrow microenvironment for myeloma cells remains an uncharted field and poorly understood.
COVID-19 and the Liver: Uncovering the Hidden Culprit behind Liver Injury
The effects of COVID-19 have been of increasing interest in all fields of medicine after the pandemic, especially considering the important impact and incidence of patients infected with coronavirus. Numerous studies have reported the vast clinical implications related to permanent organ and tissue damage after infection and long COVID.
Auditory system and COVID-19
The COVID-19 pandemic that emerged in 2020 may affect the peripheral and central auditory system. According to studies in the literature, symptoms affecting the vestibulocochlear system such as sudden hearing loss, tinnitus, and vestibular neuritis are seen in individuals with COVID -19.
Positive-DAT and autoimmune manifestations in patients with JAK2V617F mutation
Myeloproliferative neoplasms (MPN) are occasionally associated with autoimmune manifestations. The prevalence of positive direct antiglobulin test (DAT) in patients with JAK2V617F mutation is not yet known.
From molecular mechanisms to precision medicine: Transformative approaches in cirrhosis management
The rising prevalence of cirrhosis has become a significant global health concern. Cirrhosis is a leading cause of morbidity and mortality worldwide, contributing to a substantial burden on healthcare systems and economies.
A case of trigeminal neuralgia after COVID-19
The trigeminal nerve is one of twelve pairs of cranial nerves that attach to the brain. The name “trigeminal” literally means three twins and refers to the fact that the fifth cranial nerve has three major divisions: the ophthalmic (V1), the maxillary (V2), and the mandibular (V3) [1]. The trigeminal nerve is the major sensory nerve of the face and is the nerve of the first branchial arch.
Physiotherapy in Mental Health Facing the Covid-19 Pandemic
According to the International Organization of Physical Therapy in Mental Health (IOPTMH), physiotherapy in mental health is a recognized specialty of physical therapy, with a subgroup representing physiotherapists from around the world before the World Confederation of Physical Therapy (WCPT). It is implemented in different settings, in health, psychiatry and psychosomatic medicine.
Association of COVID-19 coronavirus and Kawasaki syndrome like features in 1-5 years old children
In the nightmare of the coronavirus pandemic that is spreading around the world, parents could take comfort in one thing - early reports that the virus mysteriously spares children, even though this often leads to critical illness in older people. An article published in the Journal “Pediatrics”, based on 2,143 young people in China, provides the most comprehensive evidence of the spread of the virus among children, and there is bad news and good news [1].
A commentary on telehealth and telemedicine in the COVID-19 era: A world of opportunities for the neurosurgeon
The COVID-19 pandemic has produced unprecedented conditions and difficulties for the global delivery of healthcare services. In this situation, all the healthcare employees, including neurosurgeons are facing many complexities. Telemedicine has decreased the spread of infection between neurosurgeons and patients.
Efbemalenograstim alfa, a long-acting granulocyte colony-stimulating factor, a novel dimeric G-CSF Fc fusion protein for reducing the risk of febrile neutropenia following chemotherapy
Chemotherapy?induced neutropenia (CIN) can cause life-threatening complications such as febrile neutropenia (FN) or other infections. Patients who develop FN often require prolonged hospitalizations and treatment with broad-spectrum antibiotics.
Mass food challenges in a vacant COVID-19 step-down facility: reflections on the management of anaphylaxis
A popular western misconception dating back to at least the time of President John F Kennedy is that one of the Chinese characters in the word “crisis” means opportunity. The manuscript
“Management of anaphylaxis in children undergoing oral food challenges in an adapted COVID-19 field hospital” [1] detailed a highly successful attempt to not only mitigate the effects of the crisis for
elective care brought by the COVID-19 pandemic but to seek to maximize the opportunity by better utilization and redeployment of staff allowing the team to reduce pre-pandemic waiting lists by 57%.
Vaccination, politics and COVID-19 impacts: update
In an earlier manuscript, the author found a strong relationship between political views, vaccination levels and COVID-19 death rates. This study revealed that in U.S. counties where large proportions of voters cast their ballot for Donald Trump in the 2020 presidential election, vaccination levels were lower and COVID-19 death rates were higher. This update explores this relationship six months later when more recent data are available. The updated analysis found that with the passage of time, the relationship between political views, vaccination levels and COVID-19 death rates became even stronger.
Spinal cord infarction associated with severe acute respiratory syndrome coronavirus 2: A case series of diagnostic challenges and postacute sequelae of COVID-19
Spinal cord infarction is extremely uncommon among vascular events, accounting for only 0.3-1% of all strokes and 5-8% of acute myelopathies. While deep vein thrombosis, pulmonary embolism, and stroke are commonly observed complications of COVID-19, spinal cord infarction is relatively rare.
Withstanding the COVID19 pandemic - A tertiary children’s hospital’s commitment to equitable care
Acute appendicitis is one of the most common surgical procedures performed among pediatric patients in the United States [1]. The pathophysiology of the disease begins with luminal obstruction of the appendix, leading to venous congestion, with eventual arterial inflow obstruction, and finally luminal rupture, resulting in spillage of enteric contents into the abdominal cavity.