Journal of Clinical Pediatrics and Neonatology

Proximal humerus fracture with simultaneous shoulder dislocation in children is a rare occurrence, with few reported cases. This systematic review of case reports aimed to document the outcomes of different treatment methods. A comprehensive literature search from 1980 to 2024 included case reports on traumatic shoulder fracture-dislocation in children. Eighteen studies were included, with a mean followup of 1.5 years. The cases comprised 7 boys and 11 girls, aged between 11 months and 16 years (median 6 years). The cases were divided into two groups based on epiphysealinvolvement.

Enhanced recovery after surgery (ERAS) is a comprehensive care protocol that incorporates evidence-based practices to achieve the most optimal postoperative outcomes, safe on-time discharge, and surgical cost efficiency. ERAS protocols have been adapted for specialty-specific needs and implemented by a variety of surgical disciplines including thoracic surgery.

Geophagy is described in most countries of the world as a practice observed in pregnant women. In industrialized countries, it results from migrant populations who carry with them their cultural habits and practices. This is the case in France and more particularly in Guiana, an overseas territory. Originally used to treat the ills of pregnancy, it is today considered to be dangerous for the woman and her unborn child.

HELLP syndrome (hemolysis, elevated liver blood tests and low platelets) is a serious complication in pregnancy characterized by hemolysis, elevated liver enzymes and low platelet count occurring in 0.2 to 0.6% of all pregnancies and in 10–20% of cases with severe preeclampsia

The incorporation of patient-reported outcomes (PROs) is essential for assessing whether a cancer treatment enhances overall patient well-being, beyond merely extending survival. This scoping review aimed to identify and analyze the use of PROs in ovarian cancer clinical trials.

Primary myelofibrosis (PMF) is a type of myeloproliferative neoplasm (MPN) that portends a poor prognosis and has limited options for treatment. PMF is often driven by clonal mutations in one of three genes that regulate the JAK-STAT signaling pathway, leading to hyperactivation of this signaling pathway and over-proliferation of megakaryocytes (MKs) and their precursors. PMF presents with debilitating symptoms such as splenomegaly and weight loss.

The use of left placket single muscle flap covered anastomosis in proximal gastrectomy has not been reported in the literature. The occurrence of gastroesophageal reflux after proximal gastrectomy is closely related to the mode of digestive tract reconstruction. The currently available digestive tract reconstruction approach affects patient’s postoperative quality of life due to the disadvantages of gastroesophageal reflux and anastomotic stenosis.

Optimum nutrition is the key for growth and neurodevelopment of the vulnerable preterm neonates, yet immaturity of the gut and risk of necrotizing enterocolitis in this subgroup of neonates create hesitancy regarding aggressive feeding. Feeding practices in the preterm babies are heterogeneous across various neonatal intensive care units. Many neonatal units still differ in terms of feeding intervals, volume of feed initiation and slow versus fast advancement of feeds.

Background and controlled electromagnetic radiation (EMR) on cells and tissues induces thermal, non-thermal, and dielectric property change. After EMR interaction with cells/tissues the resulting signal is used for imaging, bio-molecular response, and photo-biomodulation studies at infrared regime, and therapeutic use. We attempt to present a review of current literature with a focus to present compilation of published experimental results for each regime viz. microwave (extremely low frequency, ELF to 3 GHz), to cellular communication frequencies (100 kHz to 300 GHz), millimeter wave (300 GHz-1 THz), THz (1 THz-20THz) and the infra-red band extending up to 461 THz.

The mini-review is an update of the original article: Do bachelor assignments in Danish midwifery- and nursing educations reflect evidence-based practice? A document study [1]. We will summarize the findings from the original article, add an analysis of 140 recent bachelor assignments and present the result of a new search of literature to see recent developments in the field. Our aim is to see if the bachelor assignments present evidence-based nursing. 

Cancer biology involves complex dynamics and interactions between cells and the tissue environment. Mathematical modeling and computer simulation can provide a powerful instrument for considering this complexity. Agent-based modeling is a particular discrete hybrid modeling method.

The COVID-19 pandemic that emerged in 2020 may affect the peripheral and central auditory system. According to studies in the literature, symptoms affecting the vestibulocochlear system such as sudden hearing loss, tinnitus, and vestibular neuritis are seen in individuals with COVID -19. 

Cystinosis is a rare autosomal recessive lysosomal storage disorder, characterised by the intra-lysosomal accumulation of cystine. Cystinosis results from a defect in the CTNS protein, a lysosomal transport protein for cystine. There are three subtypes of cystinosis: infantile nephropathic cystinosis, juvenile nephropathic cystinosis and ocular non-nephropathic cystinosis.

Enteric duplication cysts are rare congenital malformations of the gastrointestinal tract that can be found anywhere along the entire alimentary canal. Duplication cysts share a muscular layer with the adjacent bowel and contain their own mucosal lining which may be that of any part of the alimentary tract. 

Osteoporosis is a worldwide disease and osteoporotic vertebral fractures (OVFs) have a high incidence in the elderly population, mostly involving female sex in the postmenopausal status. They are usually treated conservatively with a bed rest period, pain control with analgesics, bracing, bisphosphonates and early rehabilitation. Nevertheless, this kind of treatment can fail with persistent pain, collapse, pseudoarthrosis, kyphotic deformity and neurologic impairment. Therefore, there is the necessity to identify clinical, radiographic and magnetic resonance parameters that might predict risk of complications and conservative treatment failure of osteoporotic vertebral fractures.

Ischemic colitis (IC) is a common cause of severe lower gastrointestinal bleeding (LGIB) in the elderly. There are very few studies of patients with IC as a cause of severe LGIB in the literature. This article aims to review diagnosis, colonoscopic findings, medical treatment, and outcomes of patients with IC as a cause of severe hematochezia.

Activated phosphoinositide 3-kinase delta syndrome (APDS) is a rare syndrome of immune dysregulation that is inherited in an autosomal dominant fashion and results in varying severity of the clinical phenotype. APDS is a result of a gain-of-function mutation in the gene PIK3CD, which codes for a catalytic subunit of the PI3K-Delta kinase.

Neonatal cholestasis (NC) is usually a result of hepatobiliary dysfunction and can lead to extensive workup and prolonged stay in the NICU. NC is never physiological but rather a sign of hepatobiliary and/or metabolic disorders, some of which can become fatal if it is not identified and treated in time.

A series of studies suggested that hypertension is significantly associated with the risk of gallstone disease (GSD). However, due to differences in study design, population stratification, sample size, and diagnostic criteria for GSD, the results of each study are inconsistent, limiting the strength and application of these pieces of evidence. 

Described in seafarers in the 18th century, Vitamin C deficiency is the cause of the clinical syndrome that became known as ‘The Scurvy’ . Observations that dietary supplementation with citrus fruits effected a rapid cure led to organized preventative measures, and helped to establish the importance of a balanced diet in maintaining health. Vitamin C is an essential nutrient also known as Ascorbic acid, isolated in 1923, and chemically produced in 1933. This was the first example of a vitamin being developed and then used as a therapeutic pharmacological preparation .