Journal of Clinical and Experimental Hematology

In recent years, various types of synthetic cannabinoids have become widely distributed and are causing social and health problems in most parts of the world. Synthetic cannabinoids are currently the largest group of new psychoactive substances. Those that have been subjected to legal control are replaced by newer controlled and uncontrolled substances.

Background: lack of knowledge and awareness of COVID-19 and radiation safety among healthcare professionals will adversely affect their health and the patients’ safety due to unnecessary radiation exposure and rapid spread of COVID-19. The purpose of this study is to evaluate the knowledge and the awareness of both domains; COVID-19 and radiation awareness in one survey study. 

Background: Maternal hemorrhage represents the most prevalent complication and primary cause of mortality during childbirth. Extensive studies have elucidated noteworthy correlations between ABO blood type and cardiovascular disease risk in both genders. Notably, individuals with blood type O exhibit a substantial variation in the formation of the platelet plug on vascular lesions, accompanied by a reduction in von Willebrand factor.

A logic model was developed as part of an evaluation of a case management program (CMP) for frequent users in a health and social services center in the province of Québec (Canada). Five approaches were used as part of a qualitative multiple case study methodology: analysis of unpublished documents, review of literature on CMPs for frequent users, in-depth interviews, focus groups with stakeholders and participant observations. Collected data were analyzed using thematic analysis and validated by the health and social services center’s partners.

In the previous several years there has been much progress in developing more accurate thixo- lasto- visco-plastic rheological models that can be used to mechanically characterize human blood. In theory as the thixo-elasto-visco-plastic (TEVP) model accuracy and predictive capability improves, the parameterization, as well as insights and parametric correlations will also improve. 

According to the International Organization of Physical Therapy in Mental Health (IOPTMH), physiotherapy in mental health is a recognized specialty of physical therapy, with a subgroup representing physiotherapists from around the world before the World Confederation of Physical Therapy (WCPT). It is implemented in different settings, in health, psychiatry and psychosomatic medicine.

Primary central nervous system lymphoma (PCNSL) is a rare and aggressive extranodal Non Hodgkin Lymphoma. Combined modality treatment with high-dose methotrexate (HD-MTX) followed by whole brain radiotherapy (WBRT) has been a commonly used treatment approach.

The one conceptual key to improving newborn healthcare outcomes is thought to be bridging the access gap to care, particularly in sub-Saharan Africa. However, recent studies have reported conflicting results relative to establishing a link between outcomes and access to care intervention programs.

Activated phosphoinositide 3-kinase delta syndrome (APDS) is a rare syndrome of immune dysregulation that is inherited in an autosomal dominant fashion and results in varying severity of the clinical phenotype. APDS is a result of a gain-of-function mutation in the gene PIK3CD, which codes for a catalytic subunit of the PI3K-Delta kinase.

Participating in physical activity and exercise has significant benefits, including treating, preventing, and reducing risk factors for chronic conditions such as diabetes, hypertension, coronary heart disease, and osteoarthritis. Physical activity can also positively play a role in palliative care among individuals with terminal diseases. 

The superior mesenteric artery syndrome is an uncommon entity included in the spectrum of vascular syndromes. The low presentation, variety of unspecific symptoms, and shortage of bibliography presents a challenging diagnosis for both clinicians and radiologists. Our aim is to present a 63 years-old male patient with pancreatitis history and repeated symptoms. 

Individuals with spinal cord injury (SCI) have a significantly increased risk for cognitive impairment that is associated with cerebrovascular remodeling and endothelial dysfunction. The sub-acute stage following high thoracic SCI is characterized by increased fibrosis and stiffness of cerebral arteries. However, a more prolonged duration after SCI exacerbates cerebrovascular injury by damaging endothelium.

The human brain is a complex network of billions of neurons accompanied by astrocytes and microglia among others [1]. Neurons communicate via specialized sites of cell-cell contacts called synapses, where information is transmitted via the presynaptic release of neurotransmitter from synaptic vesicles (SVs) [2]. Through the integration of information transmitted via large networks of neurons, complex tasks, such as learning, memory and various behaviors, are regulated.

The increasing prevalence of drug-resistant pathogens has highlighted the need for innovative approaches in drug discovery, including drug re-purposing. Artificial intelligence (AI) has emerged as a transformative tool in this endeavor, with the potential to revolutionize not only drug re-purposing for infectious diseases but also the field of hematology.

Malan syndrome (Sotos Syndrome 2, OMIM 614753) is a rare autosomal dominant overgrowth disorder caused by either chromosome 19p13.2/19p13.13 microdeletion or Nuclear Factor 1 X-Type (NFIX) gene haploinsufficiency. Symptoms typically appear in infancy and include dysmorphic features, seizures, and behavioral issues; however, the degree of immune system involvement is not clear. Herein, we are reporting a case of Malan syndrome who presented to the immunology clinic with recurrent bacterial infections, including three episodes of pneumonia confirmed by chest X-ray.

The role of Physiotherapy is focused on rehabilitation, health promotion, and treating conditions which has resulted in issues in movement [1]. Physiotherapy in recent years is seeing an influx of patients being referred due to musculoskeletal, respiratory, and neurological conditions as a drive for healthy lifestyle, exercise, holistic approaches as well as the musculoskeletal expertise of the Physiotherapist takes center stage within the economies globally.

Immune checkpoint inhibitors (ICI) have emerged as promising treatment options for many cancers. ICIs exert their therapeutic effects by targeting immune inhibitory molecules on T-cells in adaptive immunity, such as cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), programmed cell death 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1). ICIs, however, can result in a wide variety of immune-related adverse events (iRAE), including myocarditis, a rare and potentially deadly complication that necessitates early diagnosis.

Sports have reached, now-a-days, up to the highest levels of professionalism, thus are more physically and psychologically demanding. Sports injuries are now quite widespread too. These injuries can reduce the athletes’ performance and keep them away from reaching their fullest potential. Sports medicine, a discipline of modern medicine deals with physical fitness as well as the diagnosis, treatment, and prevention of sports injuries. 

Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults. 

Enteric fever is a major public health concern in developing countries. Enteric fever can result from Salmonella typhi and Salmonella paratyphi infections after consuming contaminated food or water. The increase in widespread drug resistance is severely limiting treatment options for this serious disease. This case report covers a 23 year old patient history who got lab acquired infection of Salmonella paratyphi A infection. Initially, he experienced symptoms of fever, and irritability, which progressed to severe loose motions and high-grade fever.