Commentary Open Access

Exercise and its influence on the tumor microenvironment — the role of muscle-cancer cross talk

Dorothea Clauss , Nadira Gunasekara , Wilhelm Bloch

Exercise is increasingly being recognized as an important part of cancer treatment, as it has been shown to alleviate treatment- and disease-related side effects and improve quality of life of patients with cancer. Furthermore, exercise has been linked to a reduced risk of cancer recurrence, particularly in cases of breast and colorectal cancer. In recent years, the question has come to the forefront: “How?” does exercise influences cancer survival, and with it the interest in the underlying physiological mechanisms. 

J Cancer Biol, 2026, Volume 7, Issue 1, p1-2 | DOI: 10.46439/cancerbiology.7.081