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Journal of Biomed Research
ISSN: 2693-5910
About this Journal
Journal of Biomed Research is an international scientific peer reviewed journal having a broad scope of incorporating both clinical and basic science topics of medicine in health and diseases. The journal publishes original research articles, reviews, editorials, case reports, short communications, commentary etc. in the field of medicine and its subspecialties.
Articles
Non-invasive optical brain pulse monitoring: Experience from the first 195 patients
Continuous, non-invasive optical brain pulse monitoring (OBPM; Cyban Pty. Ltd., Melbourne, Australia) represents a significant advancement in the field of neurological monitoring. OBP monitoring uses red and infrared light sources to capture cardiac and respiratory waves from brain pulse waveforms, which reflect changes in both brain oxygen levels and brain movement.
Blinding uveitis induced by secukinumab: A case-based review
Secukinumab, a human monoclonal antibody targeting interleukin-17A (IL-17A), is widely used for treating immunoinflammatory disorders. While effective, drug-induced uveitis (DIU) is a rare but serious adverse effect associated with biologic medications like TNF-α inhibitors and more recently, IL-17 inhibitors such as secukinumab. We present a case of posterior uveitis in a 42-year-old male with AS who developed ocular symptoms two years after starting secukinumab.
Role of cellular, acellular and matrix-like products (CAMPs) in wound bed preparation in diabetic foot
Diabetic foot ulcers account for 70-80% of all ulcer cases, with this proportion rising to 21–27% in developing countries. The associated mortality rate ranges from 3.75% to 58.8%.
Clinical insights and research needs in atezolizumab induced neurotoxicity
In recent years, immune checkpoint inhibitors (ICIs) have transformed the scope of cancer treatment. Atezolizumab, is a humanized monoclonal antibody that specifically targets programmed death-ligand 1 (PD-L1) to block its interaction with PD-1 and B7-1 receptors, thereby reinstating T cell response.
Skin necrosis following dobutamine extravasation
Dobutamine is a synthetic catecholamine with activity on both alpha-1 and beta-2 adrenoceptors. It is used intravenously as an inotropic agent for short term treatment of heart failure. Dobutamine side effects involve usually cardiovascular system. Cutaneous side effects such as inflammation in the administration site following accidental extravasation could occur. Skin necrosis from intravenous soft tissue infiltration is a rare but serious complication of intravenous therapy. Herein we report a rare case of a local skin necrosis in dobutamine infusion site.
The pathogenetic roles of arachidonate 5-lipoxygenase, xanthine oxidase and hyaluronidase in inflammatory diseases: A review
Inflammation is a complex biological process essential for protecting the body from harmful stimuli. However, dysregulated or chronic inflammation can contribute to the pathogenesis of various diseases, including asthma, rheumatoid arthritis, and gout. Pro-inflammatory enzymes, such as arachidonate 5-lipoxygenase (A5-LOX), xanthine oxidase, and hyaluronidase, play key roles in the initiation, progression, and resolution of inflammation.
Drug-induced interstitial lung disease: Insights from a Tunisian case series and literature review
Drug-induced lung disease (DILD) can involve various lung parts, including the airways, lung parenchyma, pleura, vasculature, and neuromuscular system. The most prevalent form of DILD is interstitial lung disease (ILD), characterized by varying levels of inflammation and fibrosis within the lung parenchyma.
Half-time hydration and re-warm-up strategies for football players
We have read the commentary by Fernandes H (2024) with interest on a mini-review entitled Hydration Strategies for Elite Soccer Players. Given the popularity of the game globally and the busy tournament schedules without a break for the soccer players, their fitness remains a primary concern for the players and their coaches alike. Hence, elite soccer performance is crucial and depends on physiological readiness, technical skills, and tactical execution.