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Neurological biomarkers in adolescent and young adult populations with hyperuricemia and gout: diagnostic potential and clinical implications

Hyperuricemia and gout represent significant metabolic and inflammatory disorders with increasing prevalence among adolescents and young adults (typically defined as ages 12–25 years). Epidemiological studies indicate that adolescent hyperuricemia prevalence varies significantly by geographic region and diagnostic criteria, with recent studies reporting rates ranging from 8.4% to 21.4% depending on the threshold definitions applied [1].