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Commentary Open Access
Volume 5 | Issue 1 | DOI: https://doi.org/10.46439/allergy.5.040

COVID-19 in the post-vaccination era: Who is at risk of severe disease?

  • 1Allergy and Clinical Immunology Department, Hospital Juárez de México, Mexico City, Mexico
  • 2Infectious Diseases Department, Clínica Condesa Iztapalapa, Mexico City, Mexico
  • 3Infectious Diseases Department, Hospital de Infectología, Centro Médico Nacional La Raza, Mexico City, Mexico
  • 4Medical Director of Unidad Médica Zurich Satélite, Mexico, Mexico. and SLAAI President-Elect
+ Affiliations - Affiliations

Corresponding Author

Rojo-Gutiérrez María Isabel, mi_rojo@yahoo.com.mx

Received Date: November 02, 2023

Accepted Date: December 29, 2023

Abstract

Vaccination against SARS-CoV-2 began in December 2020 and with this strategy, the course of the pandemic would be modified. BNT162b2 (Pfizer–BioNTech), mRNA-1273 (Moderna), and ChAdOx1 nCoV-19 (Oxford–AstraZeneca) were the main vaccines that demonstrated a reduction in hospitalization and death from SARS-CoV-2 in clinical trials. Post-vaccination infection by COVID-19 is called breakthrough infection. Breakthrough infection is more frequent in health workers, and smokers, and critical illness is more frequent in patients with advanced age, and cardiovascular disease. Following vaccination efforts around the world, the incidence of severe COVID-19 infection has decreased, declaring the end of the pandemic by the World Health Organization. However, efforts to keep vaccination active, especially in at-risk populations, must continue.

Keywords

COVID-19, Vaccines, Breakthrough infection, Comorbidities

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