Addiction and Substance Abuse

Original Research Open Access

Decisional incentive sensitivity is linked to contingency management outcome and striatal dopamine signaling in individuals with cocaine use disorder: a preliminary study

Nehal P. Vadhan , Kenneth M. Carpenter , Elysia Benedict , Catherine E. Myers , Mark A. Gluck , Diana Martinez , Edward V. Nunes

Nontreatment-seeking individuals with cocaine use disorder (CUD) have been found to exhibit decision-making on laboratory tasks that is risky but also sensitive to monetary incentive, relative to controls. Objective: The purpose of this study was to replicate these findings in treatment-seeking individuals and explore their relationships with voucher-based treatment outcome and striatal dopamine (DA) release.

Addict Subst Abuse, 2026, Volume 4, Issue 1, p1-10 | DOI: 10.46439/addiction.4.011