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American Journal of Aging Science and Research
ISSN: 2694-4332
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Am J Aging Sci Res, 2024, Volume 4, Issue 1, p1-4 | DOI: 10.46439/aging.4.017
Environmental determinants for protein structuring and amyloid transformation
Amyloid transformation under laboratory conditions is achieved by shaking an aqueous solution of any protein. The shaking time varies significantly, demonstrating the variable degree of ease of structural transformation in a given protein. The structural specificity that distinguishes amyloid forms from biologically active proteins is the flatness (two-dimensionality) of the form of each chain in the amyloid fibril.
Am J Aging Sci Res, 2024, Volume 4, Issue 1, p5-14 | DOI: 10.46439/aging.4.018
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.
Am J Aging Sci Res, 2020, Volume 1, Issue 1, p12-19 | DOI: 10.46439/aging.1.004
Transcription factor motif activity as a biomarker of muscle aging
In prior work, we analyzed gene expression profiles of mouse, rat and human gastrocnemius muscles to identify conserved regulators of muscle aging processes. By further comparing data obtained from different muscles we found stronger conservation of aging-related factors at the level of molecular pathways than at the level of individual genes.
Am J Aging Sci Res, 2021, Volume 2, Issue 1, p19-23 | DOI: 10.46439/aging.2.010