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American Journal of Aging Science and Research
ISSN: 2694-4332
Antonia Patruno
Professor
University "G. d'Annunzio", Italy
Impact of sex on premature mortality for elderly patients with early adenocarcinoma of the esophagus or stomach
Can a study that’s not statistically significant be meaningful?
Environmental determinants for protein structuring and amyloid transformation
American Journal of Aging Science and Research is an international peer reviewed journal providing a platform for rapid publication of articles related to biology of aging, physiology of age-related diseases and research outcomes. The Journal promotes exchange of ideas across the broad audience of multidisciplinary academics and practitioners working in the field of gerontology.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Environmental determinants for protein structuring and amyloid transformation
Amyloid transformation under laboratory conditions is achieved by shaking an aqueous solution of any protein. The shaking time varies significantly, demonstrating the variable degree of ease of structural transformation in a given protein. The structural specificity that distinguishes amyloid forms from biologically active proteins is the flatness (two-dimensionality) of the form of each chain in the amyloid fibril.
The role of psychoeducation and yoga in reducing the burden of family caregivers of people with Alzheimer’s disease
The continuous increase in the elderly population and chronic health conditions present significant challenges to healthcare systems, particularly in developing countries. Among these conditions, dementia, particularly Alzheimer's disease (AD), is one of the most concerning, causing cognitive decline, behavioral changes, and progressive dependence on family caregivers.
P38 molecular targeting for next-generation kidney damage therapy
p38 MAPK is a multifunctional signaling kinase. It is a responder to stress stimuli performing various pleiotropic functions ranging from maintenance of cellular homeostasis to contributing to cellular dysfunction, depending on the tissue environment. The p38 MAPK family consists of four isoforms: p38α, p38β, p38γ, and p38δ, each with distinct roles in cellular signaling. Among these, p38α is the most extensively studied and has been implicated in the pathogenesis of various diseases due to its expression in almost all cellular types [1].
Impact of sex on premature mortality for elderly patients with early adenocarcinoma of the esophagus or stomach
Background: In a recent study, it was shown that patients with pT1 adenocarcinoma of the esophagus or stomach have a shorter survival time compared to an age- and gender-matched group from the normal population despite curative therapy. The reasons for the loss of expected life years (YLL) can only be discussed. The aim of the present evaluation is to analyze the influence of the patients' gender on the results.
Environmental determinants for protein structuring and amyloid transformation
Amyloid transformation under laboratory conditions is achieved by shaking an aqueous solution of any protein. The shaking time varies significantly, demonstrating the variable degree of ease of structural transformation in a given protein. The structural specificity that distinguishes amyloid forms from biologically active proteins is the flatness (two-dimensionality) of the form of each chain in the amyloid fibril.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Transcription factor motif activity as a biomarker of muscle aging
In prior work, we analyzed gene expression profiles of mouse, rat and human gastrocnemius muscles to identify conserved regulators of muscle aging processes. By further comparing data obtained from different muscles we found stronger conservation of aging-related factors at the level of molecular pathways than at the level of individual genes.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.
Impact of sex on premature mortality for elderly patients with early adenocarcinoma of the esophagus or stomach
Background: In a recent study, it was shown that patients with pT1 adenocarcinoma of the esophagus or stomach have a shorter survival time compared to an age- and gender-matched group from the normal population despite curative therapy. The reasons for the loss of expected life years (YLL) can only be discussed. The aim of the present evaluation is to analyze the influence of the patients' gender on the results.
The role of psychoeducation and yoga in reducing the burden of family caregivers of people with Alzheimer’s disease
The continuous increase in the elderly population and chronic health conditions present significant challenges to healthcare systems, particularly in developing countries. Among these conditions, dementia, particularly Alzheimer's disease (AD), is one of the most concerning, causing cognitive decline, behavioral changes, and progressive dependence on family caregivers.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Transcription factor motif activity as a biomarker of muscle aging
In prior work, we analyzed gene expression profiles of mouse, rat and human gastrocnemius muscles to identify conserved regulators of muscle aging processes. By further comparing data obtained from different muscles we found stronger conservation of aging-related factors at the level of molecular pathways than at the level of individual genes.
Cultural context and social engagement of Third Age adults
Third Age adults are able to engage in society in ways inaccessible to previous generations of older adults, ways facilitated by today’s unique cultural context of late modernity. The combination of myriad personal strengths and specific cultural context raises the challenge of whether and how these adults want to and can play a role in their societies.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.