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American Journal of Aging Science and Research
ISSN: 2694-4332


Nikolai Timchenko
Professor
Cincinnati Children’s Hospital Medical Center, USA
Impact of sex on premature mortality for elderly patients with early adenocarcinoma of the esophagus or stomach
Can a study that’s not statistically significant be meaningful?
Environmental determinants for protein structuring and amyloid transformation
American Journal of Aging Science and Research is an international peer reviewed journal providing a platform for rapid publication of articles related to biology of aging, physiology of age-related diseases and research outcomes. The Journal promotes exchange of ideas across the broad audience of multidisciplinary academics and practitioners working in the field of gerontology.
Psychoeducational support for family caregivers of people with dementia: implementation strategies for low- and middle-income countries
Background: Dementia caregiving in low- and middle-income countries (LMICs) occurs in contexts where public care infrastructure is limited, placing the primary responsibility for daily care on family caregivers. Psychoeducational interventions have emerged as a central strategy to strengthen coping, communication skills, and emotional well-being.
Molded soft meals in creating positive mealtime experiences for nursing home residents in Singapore
Background: Dysphagia affects an estimated 58,000 to 174,000 older adults—approximately one in seven individuals aged 65 and above. This condition poses significant physical, psychological, and social challenges that can compromise the quality of life in Singapore, which is projected to become a super-aged society this year.
Social isolation and loneliness in older adults: A growing public health challenge with evidence from Nepal
Social isolation and loneliness are increasingly recognized as major public health concerns in ageing populations, yet they remain under-addressed in low- and middle-income countries. This article examines the definitions, epidemiology, health consequences, and evidence-based responses related to social isolation and loneliness among older adults, with focused attention to Nepal.
Environmental determinants for protein structuring and amyloid transformation
Amyloid transformation under laboratory conditions is achieved by shaking an aqueous solution of any protein. The shaking time varies significantly, demonstrating the variable degree of ease of structural transformation in a given protein. The structural specificity that distinguishes amyloid forms from biologically active proteins is the flatness (two-dimensionality) of the form of each chain in the amyloid fibril.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Transcription factor motif activity as a biomarker of muscle aging
In prior work, we analyzed gene expression profiles of mouse, rat and human gastrocnemius muscles to identify conserved regulators of muscle aging processes. By further comparing data obtained from different muscles we found stronger conservation of aging-related factors at the level of molecular pathways than at the level of individual genes.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.
Impact of sex on premature mortality for elderly patients with early adenocarcinoma of the esophagus or stomach
Background: In a recent study, it was shown that patients with pT1 adenocarcinoma of the esophagus or stomach have a shorter survival time compared to an age- and gender-matched group from the normal population despite curative therapy. The reasons for the loss of expected life years (YLL) can only be discussed. The aim of the present evaluation is to analyze the influence of the patients' gender on the results.
The role of psychoeducation and yoga in reducing the burden of family caregivers of people with Alzheimer’s disease
The continuous increase in the elderly population and chronic health conditions present significant challenges to healthcare systems, particularly in developing countries. Among these conditions, dementia, particularly Alzheimer's disease (AD), is one of the most concerning, causing cognitive decline, behavioral changes, and progressive dependence on family caregivers.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Transcription factor motif activity as a biomarker of muscle aging
In prior work, we analyzed gene expression profiles of mouse, rat and human gastrocnemius muscles to identify conserved regulators of muscle aging processes. By further comparing data obtained from different muscles we found stronger conservation of aging-related factors at the level of molecular pathways than at the level of individual genes.
Cultural context and social engagement of Third Age adults
Third Age adults are able to engage in society in ways inaccessible to previous generations of older adults, ways facilitated by today’s unique cultural context of late modernity. The combination of myriad personal strengths and specific cultural context raises the challenge of whether and how these adults want to and can play a role in their societies.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.