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American Journal of Aging Science and Research
ISSN: 2694-4332


Nikolai Timchenko
Professor
Cincinnati Children’s Hospital Medical Center, USA
Impact of sex on premature mortality for elderly patients with early adenocarcinoma of the esophagus or stomach
Can a study that’s not statistically significant be meaningful?
Environmental determinants for protein structuring and amyloid transformation
American Journal of Aging Science and Research is an international peer reviewed journal providing a platform for rapid publication of articles related to biology of aging, physiology of age-related diseases and research outcomes. The Journal promotes exchange of ideas across the broad audience of multidisciplinary academics and practitioners working in the field of gerontology.
A new paradigm of the biodynamic of cephalospinal fluid based on the unsuspected capacity of human cells to dissociate water molecules: Implications in ageing processes
Cephalospinal fluid (CSF) dynamics (secretion and absorption) rate is considered a primary disturbance in the CSF dynamics. CSF reabsorption is a key part of ventriculomegaly, and to a lesser extent other anatomical features of CNS such as elasticity, brain water content, glial cell ratio, tissue atrophy, cranial suture status, age, weight, height, and sex.
Falls in older people: A global public health concern
Background: Falls are the second leading cause of unintentional injury deaths among older adults, often resulting in fractures, disability, loss of independence, and increased mortality. Aim: This review explores the global burden of falls, highlights risk factors and regional disparities, and examines prevention and policy strategies with a focus on LMICs.
Environmental determinants for protein structuring and amyloid transformation
Amyloid transformation under laboratory conditions is achieved by shaking an aqueous solution of any protein. The shaking time varies significantly, demonstrating the variable degree of ease of structural transformation in a given protein. The structural specificity that distinguishes amyloid forms from biologically active proteins is the flatness (two-dimensionality) of the form of each chain in the amyloid fibril.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Transcription factor motif activity as a biomarker of muscle aging
In prior work, we analyzed gene expression profiles of mouse, rat and human gastrocnemius muscles to identify conserved regulators of muscle aging processes. By further comparing data obtained from different muscles we found stronger conservation of aging-related factors at the level of molecular pathways than at the level of individual genes.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.
Impact of sex on premature mortality for elderly patients with early adenocarcinoma of the esophagus or stomach
Background: In a recent study, it was shown that patients with pT1 adenocarcinoma of the esophagus or stomach have a shorter survival time compared to an age- and gender-matched group from the normal population despite curative therapy. The reasons for the loss of expected life years (YLL) can only be discussed. The aim of the present evaluation is to analyze the influence of the patients' gender on the results.
The role of psychoeducation and yoga in reducing the burden of family caregivers of people with Alzheimer’s disease
The continuous increase in the elderly population and chronic health conditions present significant challenges to healthcare systems, particularly in developing countries. Among these conditions, dementia, particularly Alzheimer's disease (AD), is one of the most concerning, causing cognitive decline, behavioral changes, and progressive dependence on family caregivers.
Can a study that’s not statistically significant be meaningful?
In ongoing efforts to bring innovation to healthcare, technology and patient self-management are at an important intersection. Our study, "A Mobile App for Chronic Disease Self-Management for Individuals with Low Health Literacy: A Multisite Randomized Controlled Clinical Trial” [1], serves as a potentially useful contribution to this intersection by addressing the challenges faced by older adults with chronic conditions and low health literacy in managing chronic health conditions.
Transcription factor motif activity as a biomarker of muscle aging
In prior work, we analyzed gene expression profiles of mouse, rat and human gastrocnemius muscles to identify conserved regulators of muscle aging processes. By further comparing data obtained from different muscles we found stronger conservation of aging-related factors at the level of molecular pathways than at the level of individual genes.
Cultural context and social engagement of Third Age adults
Third Age adults are able to engage in society in ways inaccessible to previous generations of older adults, ways facilitated by today’s unique cultural context of late modernity. The combination of myriad personal strengths and specific cultural context raises the challenge of whether and how these adults want to and can play a role in their societies.
Association between physical function and perceived stress among U.S. Chinese older adults
Objectives: Physical function impairment can cause great stress to older adults. The purpose of the study is to investigate the association between self-reported and directly-observed physical function on perceived stress among U.S. Chinese older adults.