Archives of Alzheimer's & Parkinson's Disease

Alzheimer's and Parkinson's diseases are two of the most prominent and complex progressive neurological disorders that have a profound global impact [1,2]. These diseases affect millions of individuals worldwide, causing significant morbidity and placing a substantial burden on healthcare systems and society [3,6]. Despite considerable advancements in understanding these disorders over the years, developing effective treatments remains a complex and multifaceted challenge [7,8].

National studies of Parkinson’s disease (PD) provide critical data for healthcare planning, yet methodological limitations continue to undermine their utility. This review examines recent epidemiological work, including the Greek nationwide analysis, to highlight three priority areas for refinement: diagnostic accuracy, survival methodology, and recognition of disease heterogeneity.