Journal of Clinical and Experimental Reproductive Medicine

Original Research Open Access

Autologous platelet-rich plasma to improve reproductive outcomes in women with diminished ovarian reserves: a prospective pilot study

Michelle Jia Min Loh , Yiping Fan , See Ling Loy , Ker Yi Wong , Chee Wai Ku , Tat Xin Ee , Tse Yeun Tan , Veronique Viardot-Foucault , Shuling Liu , Sadhana Nadarajah , Seong Feei Loh , Jerry Kok Yen Chan

Objective: To investigate if intraovarian autologous platelet-rich plasma (PRP) infusion improve ovarian reserve markers and fertility outcomes in women with diminished ovarian reserve (DOR).
Methods: A single-arm, prospective intervention study was conducted between July 2023 and April 2024. Women aged 21–40 years with DOR and previous poor response to maximal ovarian stimulation during IVF were recruited. 

J Clin Exp Reprod Med, 2026, Volume 3, Issue 1, p1-9 | DOI: 10.46439/reproductivemed.3.010