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Journal of Experimental Nephrology
ISSN: 2767-3383
Latest Articles
Analysis of chronic kidney disease on diagnosis, treatment, prognosis and related risk factors in patients with lymphoma: A mini-review
Bowen Qin , Xiaoqin Liu , Hui Zhang , Hairui Zhao , Xiuxi Zhou , Zhanpeng Wang , Manyi Wu , Chunyu Pan , Xiaojing Cai , Jielian Wang , Junhua Li
Currently, the field of tumor nephrology continues to evolve, and the interplay between chronic kidney disease (CKD) and lymphoma merits further investigation. The incidence of CKD among lymphoma patients is substantial, posing a significant long-term risk for CKD progression. CKD should be regarded as an independent prognostic factor for mortality in lymphoma patients. In this mini-review, we aim to extend the research direction outlined in "Diagnosis and Treatment of Secondary Nephrotic Syndrome with Rash as the Initial Symptom: A Case Report", with a focus on elucidating the correlation between CKD and lymphoma.
J Exp Nephrol, 2025, Volume 5, Issue 1, p1-5 | DOI: 10.46439/nephrology.5.016
Clinical and urodynamic findings in children and adolescents with refractory neurogenic bladder undergoing augmentation cystoplasty
Otávio Augusto Fonseca Reis , Eleonora Moreira Lima , José de Bessa Junior , Roberta Vasconcellos Menezes de Azevedo , Estella Danielle Martins Moreira , Julia de Oliveira e Sousa , Mônica Maria de Almeida Vasconcelos , Flávia Cristina de Carvalho Mrad
Augmentation cystoplasty (AC) is a surgical procedure for patients with refractory neurogenic bladder (NB). This study aimed to evaluate urinary incontinence (UI), vesicoureteral reflux (VUR), and urodynamic parameters in patients’ post-AC and compare these results to preoperative data.
J Exp Nephrol, 2025, Volume 5, Issue 1, p6-11 | DOI: 10.46439/nephrology.5.017
Difficulties of diagnosing hyponatremia disorders. Overcoming limitations with a 3-step approach and web-based diagnostic application
Kenrick Berend , Tomas Tiemen Rutger Heldeweg , Micah Liam Arthur Heldeweg
Hyponatremia presents a complex diagnostic challenge due to its broad differential diagnosis and the difficulties of its evaluation. The available diagnostic algorithms often have substantial limitations. Therefore, clinicians frequently struggle to distinguish the underlying causes of hyponatremia, leading to diagnostic and management errors that contribute to considerable morbidity and mortality.
J Exp Nephrol, 2025, Volume 5, Issue 1, p12-26 | DOI: 10.46439/nephrology.5.018
Association of fundus damage, renal function deterioration, and ferroptosis in chronic kidney disease patients
Lingli Zeng , Yan Hao , Min Tang
Introduction: This study aimed to explore the changes in ferroptosis markers and their relationship with fundus lesion severity in chronic kidney disease (CKD). Methods: We enrolled 118 CKD patients and collected clinical, renal function, fundus imaging data, and ferroptosis markers. We performed correlation and regression analyses between renal dysfunction and fundus lesions, and assessed the changes and mediating roles of serum iron (Fe), malondialdehyde (MDA), and reduced glutathione (GSH) in CKD deterioration and retinal damage.
J Exp Nephrol, 2025, Volume 5, Issue 1, p27-33 | DOI: 10.46439/nephrology.5.019