Journal of Radiation Research and Imaging

Original Research Open Access

Comparative evaluation of diffusion-weighted MRI and 18F-FDG PET-CT for detection and volumetric assessment of colorectal cancer liver metastases

Numan C. Balci , Giuseppe Iuppa , Ayham K. Ansari , Carla Hajj , Amanullah Khan , Juan S. Barajas-Gamboa , Hidayath A. Ansari

Purpose: To compare diffusion-weighted imaging (DWI) and 18F-FDG PET-CT for detection and volumetric assessment of colorectal cancer liver metastases, evaluating the optimal b-value for volumetric correlation with metabolic tumor volume (MTV). Materials and Methods: This retrospective study included 50 patients with histopathologically confirmed colorectal adenocarcinoma and liver metastases who underwent both PET-CT and liver MRI (including DWI at b=50, 400, 800 s/mm²) within 30 days. Synthetic DWI images at b=1000, 1500, and 2000 s/mm² were generated.

J Radiat Res Imaging, 2026, Volume 4, Issue 1, p1-9 | DOI: 10.46439/radiation.4.012