Diabetic Retinopathy (DR) is a leading cause of blindness in the U.S. However, not much is known of underlying molecular mechanism and how oxidative stress contributes to its development. In the present study, we investigated the involvement of TGFβ signaling pathway on the effect of oxidative stress on VEGF secretion and viability of retinal cells. VEGF is the hallmark that exacerbates DR progression in prolonged diabetes. Some major concerns that have arisen are the underlying effects of antioxidants in elevating VEGF secretion in diabetes.

In recent years, stress and stress-coping mechanisms constitute a growing public healthcare issue concerning modern society. Experiencing stress engenders a great complex mechanism named stress response, which consists of a rapid release of catecholamines by the sympathetic nervous system, followed by a slower response in which hormones, mainly glucocorticoids (GCs), are synthesized and released to the bloodstream.

In a recent issue of the Children and Youth Services Review, I published an article examining systems of support for LGBTQ youth transitioning from foster care to emerging adulthood [1]. The methodology I used to gather this data included in-depth interviewing combined with ecomapping techniques that I modified to identify the strength and structure of LGBTQ youths’ support networks. 

Sickle cell disorder (SCD) remains a disease of public interest, accounting for a significant number of deaths, especially in low and middle-income countries in Africa. Despite years of intensive studies, its cure remains a subject of ongoing investigation.

Levels of disability and health-related work absence continue to increase, yet the risk assessment and modern medicine aimed at mitigating ill health and work absence also continues to increase. There is evidence to suggest that the interaction between health and work, the economic work loss, and the influence of long-term sickness absence on health and social inequality is an important consideration for researchers and clinicians in healthcare.