Commentary Open Access
Precision targeting of the kinome: clinical progress, biological complexities, and future directions of protein kinase inhibitors
Bashir Ahmad Dar1,*, Asif Hamid Dar2, Shamim Ahmad Dar3
- 1Department of Chemistry, Government Degree College, Uri, Baramulla, 193123, J&K, India
- 2Department of Botany, Government Degree College, Uri, Baramulla, 193123, J&K, India
- 3Department of Zoology, Government Degree College Sogam 192231, India
Corresponding Author
Bashir Ahmad Dar, bashir_15_dar@yahoo.com
Received Date: December 08, 2025
Accepted Date: December 29, 2025
Dar BA, Dar AH, Dar SA. Precision targeting of the kinome: clinical progress, biological complexities, and future directions of protein kinase inhibitors. J Allergy Infect Dis. 2026;7(1):5-9.
Copyright: © 2026 Dar BA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Precision targeting of the kinome: clinical progress, biological complexities, and future directions of protein kinase inhibitors
Protein kinases are at the core of cellular communication, and they essentially control cell survival, metabolism, immune activation, and proliferation, among other things, through reversible phosphorylation. The dysregulation of kinase signaling has been identified as a key driver at the molecular level of cancer, autoimmune diseases, chronic inflammations, cardiovascular diseases, and infectious pathogenesis.