In an earlier manuscript, the author found a strong relationship between political views, vaccination levels and COVID-19 death rates. This study revealed that in U.S. counties where large proportions of voters cast their ballot for Donald Trump in the 2020 presidential election, vaccination levels were lower and COVID-19 death rates were higher. This update explores this relationship six months later when more recent data are available. The updated analysis found that with the passage of time, the relationship between political views, vaccination levels and COVID-19 death rates became even stronger.

The most significant global public health issue is still COVID-19. Due to the advent of a new variation and the widespread use of COVID-19 immunization, the disease is currently not as severe as it was in 2020. The immunization is still required, though. Here, the authors examine and offer suggestions for COVID-19 immunization as the illness transitions from an epidemic to an endemic condition.

India has an estimated population of 1.39199 billion and current vaccination approach plans to cover adult population (>18 y, about 67.53%) very soon. As on 24 December 2021, the country completed about 1.41 billion doses of COVID-19 vaccines, in about eleven months since the drive began.

Objective: Need to control the COVID-19 pandemic resurgence is a priority in India which has an estimated population of 1.39199 billion. Immunity whether acquired by recovery or vaccine, controls an infectious disease epidemic. In case of COIVD-19, the latter is more desirable. The objective of this study is to answer a research question “What is the impact of current vaccination drive in adults in generating vaccine-induced immunity in India?”

Vaccination against SARS-CoV-2 began in December 2020 and with this strategy, the course of the pandemic would be modified. BNT162b2 (Pfizer–BioNTech), mRNA-1273 (Moderna), and ChAdOx1 nCoV-19 (Oxford–AstraZeneca) were the main vaccines that demonstrated a reduction in hospitalization and death from SARS-CoV-2 in clinical trials. Post-vaccination infection by COVID-19 is called breakthrough infection.