Current Rheumatology Research

Bernhard RYFFEL

CNRS, University, Orleans

France

Academic Editor

Biography

Medical education in Bern and Geneva, MD 1978. PhD 1984 and FMH in pathology 1988 in Basel. Positions held: 1974 Immunology University of Bern, 1979 Pharmacology Sandoz Pharma Basel, 1991 University of Zurich, Pharmacology-Toxicology, 1995, Immunology University Cape Town, RSA. Since 2001 Director of research, CNRS Immunology, Orleans, France with active research, and advisor of several pharmaceutical companies. Founder of Artimmune SAS and Phenotec AG.

Research Interest

Mechanisms of inflammation, especially respiratory inflammation, fibrosis, emphysema and COPD, but also in skin, hepatic, intestinal, renal and CNS inflammation. Cell death, innate immune danger sensing and cGAS/STING, ROS and Inflammasome activation in models of human inflammatory diseases and tumor development, role of microbiome, metabolome, neuroinflammation/degeneration and ageing. Role of TNF and IL-1 members, in cell death and IL-33 and T2 / T17 polarization and differentiation. PB drug candidate Stable butyrate to treat chronic inflammatory disease.