Current Rheumatology Research

Background/Purpose: The significance of Dense Fine Speckled (DFS) pattern Anti-nuclear antibodies (ANA) by indirect mmunofluorescence (IIF) is unclear in the existing research. We aimed to investigate associations between positive ANA with DFS pattern and multiple autoimmune and rheumatic conditions.

Primary Sjögren’s syndrome (pSS) is an autoimmune rheumatic disease characterized by a lymphocytic infiltration of exocrine glands. It mostly becomes apparent in women between 40 and 60 years old. Its clinical manifestations are heterogeneous, ranging from sicca syndrome to extra glandular manifestations.

Background/Purpose: The significance of Dense Fine Speckled (DFS) pattern Anti-nuclear antibodies (ANA) by indirect mmunofluorescence (IIF) is unclear in the existing research. We aimed to investigate associations between positive ANA with DFS pattern and multiple autoimmune and rheumatic conditions.

Primary Sjögren’s syndrome (pSS) is an autoimmune rheumatic disease characterized by a lymphocytic infiltration of exocrine glands. It mostly becomes apparent in women between 40 and 60 years old. Its clinical manifestations are heterogeneous, ranging from sicca syndrome to extra glandular manifestations.

Clinical features are known to influence pain in patients, but demographic characteristics have been less studied. The aim of this cross-sectional study was to evaluate the relationship of distance to exercise facilities and other demographic factors to the pain and function score, RAPID3 (Routine Assessment of Patient Index Data) in a large rheumatology practice. 

Yao syndrome (YAOS) is a NOD2-associated autoinflammatory disease marked by periodic fevers, dermatitis, polyarthritis, distal extremity swelling, and nearly universal gastrointestinal symptoms. A recent study was the first to comprehensively assess the gastrointestinal symptoms and manifestations of YAOS, finding that most testing is normal, without gastrointestinal mucosal inflammation, and many patients have constipation and rectal evacuation disorders.

Background/Purpose: The significance of Dense Fine Speckled (DFS) pattern Anti-nuclear antibodies (ANA) by indirect mmunofluorescence (IIF) is unclear in the existing research. We aimed to investigate associations between positive ANA with DFS pattern and multiple autoimmune and rheumatic conditions.