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Archives of Autoimmune Diseases
ISSN: 2767-3340
Featured Articles
"I see the light": The role of seasonal photo period in the development of immune regulation, a potential explanation for the latitude gradient of autoimmunity and allergy
Margaret S. Clark
Prevalence of common autoimmune diseases such as multiple sclerosis (MS), type 1 diabetes, rheumatoid arthritis, and inflammatory bowel disease and allergies such as food allergies or eczema affect approximately 20% of the human population.
Arch Autoimmune Dis, 2025, Volume 5, Issue 1, p1-6 | DOI: 10.46439/autoimmune.5.016
Adiponectin receptor fragmentation in mouse models of type 1 and type 2 diabetes
Dylan Frabutt, Natalie Stull, Annie R. Pineros, Sarah A. Tersey, Donalyn Scheuner, Teresa L. Mastracci, Michael J. Pugia
The protein hormone adiponectin regulates glucose and fatty acid metabolism by binding to two PAQR-family receptors (AdipoR1 and AdipoR2). Both receptors feature a C-terminal segment which is released by proteolysis to form a freely circulating C-terminal fragment (CTF) found in the plasma of normal individuals but not in some undefined diabetes patients.
Arch Autoimmune Dis, 2020, Volume 1, Issue 1, p3-13 | DOI: 10.46439/autoimmune.1.002
Utilization of electronic health records for the assessment of adiponectin receptor autoantibodies during the progression of cardio-metabolic comorbidities
Michael J. Pugia, Meeta Pradhan, Rong Qi, Doreen L. Eastes, Anna Vorsilak, Bradley J. Mills, Zane Baird, Aruna Wijeratne, Scott M. McAhren, Amber Mosley, Anantha Shekhar, Daniel H. Robertson
Diabetes is a complex, multi-symptomatic disease whose complications drives increases in healthcare costs as the diabetes prevalence grows rapidly world-wide. Real-world electronic health records (EHRs) coupled with patient biospecimens, biological understanding, and technologies can characterize emerging diagnostic autoimmune markers resulting from proteomic discoveries.
Arch Autoimmune Dis, 2020, Volume 1, Issue 1, p17-27 | DOI: 10.46439/autoimmune.1.004