International Journal of Cardiology and Cardiovascular Diseases

Original Research Open Access

High-resolution 3D fluorescent imaging of intact tissues

Danny El-Nachef, Amy M. Martinson, Xiulan Yang, Charles E. Murry, W. Robb MacLellan

Histological analysis of fluorescently labeled tissues has been a critical tool to understand molecular organization in situ. However, assessing molecular structures within large cells and in the context of human organ anatomy has been challenging because it requires penetration of staining reagents and light deep into opaque tissues, while also conforming to the spatial constraints of high-resolution objective lenses.

Int J Cardiol Cardiovasc Dis, 2021, Volume 1, Issue 1, p1-14 | DOI: 10.46439/cardiology.1.001

Commentary Open Access

Mechanisms of troponin release into serum in cardiac injury associated with COVID-19 patients

R. John Solaro, Paola C. Rosas, Paulina Langa, Chad M. Warren, Beata M. Wolska, Paul H. Goldspink

In the early phases of the pandemic caused by the SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2) the emphasis of diagnosis and treatment was on acute respiratory distress syndrome (ARDS).

Int J Cardiol Cardiovasc Dis, 2021, Volume 1, Issue 2, p41-47 | DOI: 10.46439/cardiology.1.006