Loading
Journal of Neurobiology and Physiology
ISSN: 2692-546X
Latest Articles
Evaluation of chondrocyte dedifferentiation mechanisms using confocal Raman microscopy
N’Dré Jean N’DRE , Papa Abdou LECOR , ASSOUMOU AA , BLOHOUA MJJ
Human chondrocytes were isolated from articular cartilage harvested from a patient's knee during surgery, following informed consent. Cells were enzymatically digested with collagenase, then expanded directly onto Calcium Fluoride (CaF2) slides in two-dimensional (2D) monolayer cultures. Evaluations using wide-field optical microscopy, as well as Raman spectral measurements at D7, D14, D21, and D28 were performed for each passage from P1 to P4.
Commentary on “Understanding bacterial chondronecrosis with osteomyelitis (BCO) in poultry: Highlights from proteomic analyses and imaging techniques”
Elizabeth S. Greene , Hans Adriaensen , Frederic Elleboudt , Joëlle Dupont , Sami Dridi
Bacterial chondronecrosis with osteomyelitis (BCO) is a leading cause of lameness in broiler chickens, which results in financial losses due to mortality and reduced growth. Due to the nature of the condition, it raises animal welfare and food safety concerns as well. The pathology in the commercial setting is derived from a combination of weak bone and bacterial translocation and infection.
J Neurobiol Physiol, 2024, Volume 5, Issue 1, p9-14 | DOI: 10.46439/neurobiology.5.025
The genetical genomic path to understanding why rats and humans consume too much alcohol
Boris Tabakoff , Paula L. Hoffman , Laura M. Saba
At the invitation of the Journal, we are providing a summary of our published work that has followed the publication in 2009 of our manuscript entitled “Genetical Genomic Determinants of Alcohol Consumption in Rats and Humans”. Our initial premise, which has been maintained throughout, is that knowledge regarding gene transcription would greatly enhance GWAS of alcohol-related phenotypes.
J Neurobiol Physiol, 2024, Volume 5, Issue 1, p15-22 | DOI: 10.46439/neurobiology.5.026
Commentary on “Identification of CD19 as a shared biomarker via PPARγ/β-catenin/Wnt3a pathway linking psoriasis and major depressive disorder”
Bin Zhou , Zhujun Ma , Jiahao Yang , Lingui Li , Hanying Ma
This study presents a comprehensive exploration into the shared molecular mechanisms linking psoriasis and major depressive disorder (MDD), two conditions that are increasingly recognized as having potential comorbidities. It offers new insights into the immune and genetic pathways that may contribute to both disorders, emphasizing the potential of CD19 as a biomarker and therapeutic target through the PPARγ/β-catenin/Wnt3a signaling pathway.
J Neurobiol Physiol, 2024, Volume 5, Issue 1, p23-25 | DOI: 10.46439/neurobiology.5.027