It may seem irony that nutrition science historically pertained mostly to undernutrition and deficiency syndromes [1] but nowadays prevention, control and treatment of overnutrition, manifested as overweight and obesity, has become the main task of most nutritionists and related professionals [2]. 

An ancient proverb like “we are what we eat”, entails the significance and an influence of dietary habits and thereby nutrients on all living beings. A universal system encompasses various categories of classes that recognize consequences of various diets on immunity and thereby on the health of an individual. These mechanisms mainly consist of epigenetic machineries, metabolic pathways, circadian rhythms, and diet-responsive effectors. In this light, various clinical studies exhibit immune-modulatory and beneficial effects of interceding nutrients on various diseases.

This is a comment on the article “Gender-related patterns of psychiatric disorder clustering among bariatric surgery candidates: A latent class analysis”, by Duarte-Guerra et al., J. Affect. Disord. 2018.  The study applied multivariate statistical analysis – the latent class analysis – to determine clusters of patients with obesity III (n = 393), based on their psychiatric diagnosis. Key findings indicated that most of patients were symptomatic and presented comorbid patterns of psychiatric disorders before undertaking surgery.  The patterns were mixed anxiety-bipolar disorders (47%) and anxiety-depression (up to 25%).

Complement proteins constitute a proinflammatory system of the innate immunity which bridges with the adaptive immunity. It comprises of a group of serum zymogens, complement regulatory proteins (Cregs) and receptors.

Rheumatoid arthritis (RA) is chronic inflammatory arthritis characterized by the inflammation of multiple joints and significant joint destruction and disability. It is the most common form of inflammatory arthritis that affects synovial joints.