Abstract
Background: Brucellosis is a zoonotic bacterial infection caused by the Brucella species, prevalent in various regions of Saudi Arabia, posing public health challenges. Transmission occurs primarily through consumption of unpasteurized dairy products and direct contact with infected animals. Understanding regional prevalence of Brucellosis within Saudi Arabia is crucial for developing targeted interventions.
Objective: This meta-analysis assesses the prevalence of Brucellosis across different regions of Saudi Arabia, analyzing data from various epidemiological studies to determine disease distribution and burden.
Methods: A comprehensive search was conducted in PubMed and Google Scholar without restrictions on publication dates, focusing on English-language studies. Articles reporting the prevalence of Brucellosis in Saudi Arabia or its regions were included, provided they involved human participants. Data was extracted from eligible studies, and the prevalence rates were pooled using a random-effects model to account for variability across studies.
Results: The analysis revealed significant heterogeneity in Brucellosis prevalence across different regions of Saudi Arabia. Pooled prevalence was 4% (95% CI: 0.00–0.08), with higher rates observed in the Central Region and lower rates in Western and Southern regions. Studies included varied in design and sample size, contributing to the observed regional differences.
Conclusion: This meta-analysis highlights uneven distribution of Brucellosis prevalence in Saudi Arabia, with certain regions showing significantly higher rates. Findings suggest a need for region-specific public health strategies and further research to better understand the factors contributing to these disparities. A more intensive national study could provide a clearer picture of the disease's burden, guiding effective control measures.
Keywords
Brucellosis, Brucella, Prevalence, Saudi Arabia, Meta-analysis