Interventional Pulmonology

Research Article Open Access

Potential enhanced association between obstructive lung disease and history of depression in patients with diabetes

Maria E Ramos-Nino, Charles D MacLean, Benjamin Littenberg

Depression is one of the most common comorbidities of chronic diseases including diabetes and obstructive lung diseases (emphysema, chronic bronchitis, and asthma). Obstructive lung diseases and depression have few symptoms in common. However, they are both common in adults and associated with chronic inflammation. It is not clear if their coappearance in diabetic patients is coincidental or associated beyond that expected by chance.

Interv Pulmonol, 2023, Volume 1, Issue 1, p1-4 | DOI: 10.46439/Pulmonology.1.001

Research Article Open Access

Association between the prevalence of obstructive lung disease and the use of aspirin in a diabetic population

Maria E Ramos-Nino, Charles D MacLean, Benjamin Littenberg

Aspirin (acetylsalicylic acid), a non-steroidal anti-inflammatory drug, inhibits cyclooxygenases (COX-1 and COX-2), which catalyze the conversion of arachidonic acid to prostaglandins. In control environments, low-dose aspirin (75 mg or 81 mg) inhibits COX-1 and disrupts the production of thromboxane, reducing platelet aggregation

Interv Pulmonol, 2023, Volume 1, Issue 1, p5-10 | DOI: 10.46439/Pulmonology.1.002