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Interventional Pulmonology

Research Article Open Access
Volume 1 | Issue 1 | DOI: https://doi.org/10.46439/Pulmonology.1.002

Association between the prevalence of obstructive lung disease and the use of aspirin in a diabetic population

Maria E Ramos-Nino1,2*, Charles D MacLean3, Benjamin Littenberg3
  • 1St. George’s University, Department of Microbiology, Immunology, and Pharmacology, Grenada, West Indies
  • 2Department of Pathology and Laboratory Medicine, University of Vermont 05401, Burlington, Vermont, USA
  • 3Department of Medicine, University of Vermont, Burlington, Vermont 05401, USA
+ Affiliations - Affiliations

Corresponding Author

Maria E Ramos-Nino, mramosni@sgu.edu

Received Date: May 06, 2022

Accepted Date: May 20, 2022

Citation:

Ramos-Nino ME, MacLean CD, Littenberg B. Association between the prevalence of obstructive lung disease and the use of aspirin in a diabetic population. Interv Pulmonol. 2022;1(1):5-10.


Copyright: © 2022 Ramos-Nino ME, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Many diabetic patients take a daily low-dose of aspirin because they are two to three times more likely to suffer from heart attacks and strokes, but its role in obstructive lung diseases is less clear.

Methods: A total of 1,003 subjects in community practice settings were interviewed at home. Patients self-reported their personal and clinical characteristics, including any history of obstructive lung disease (including COPD or asthma). Current medications were obtained by the direct observation of medication containers. We performed a cross-sectional analysis of the interviewed subjects to assess for a possible association between obstructive lung disease history and the use of aspirin.

Results: In a multivariate logistic regression model, a history of obstructive lung disease was significantly associated with the use of aspirin even after correcting for potential confounders, including gender, low income (

Conclusion: These data suggest a negative correlation between the use of aspirin and obstructive lung disease prevalence in patients with diabetes but not for those that use insulin. Further studies are required to determine if this association is causal.

Keywords

Obstructive lung disease, Asthma, COPD; Aspirin, VDIS, Diabetes

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