Angiopoietin-like 4 (ANGPTL4) is a multifaceted secreted protein discovered by three different institutions in 2000 simultaneously [1]. It is expressed in adipose tissues, liver, muscle, heart, kidney, skin, and other tissues. The nutritional, metabolic, and inflammatory status of the organism regulate the expression of ANGPTL4 [2-4].

Metabolic dysfunction-associated steatotic liver disease (MASLD) is comprised of a spectrum of conditions, which is a progressive form of liver disease ranging from simple steatosis to steatohepatitis. The liver regulates fat metabolic homeostasis through de novo lipogenesis, fatty acid uptake and oxidation, low-density lipoprotein secretion in hepatocytes.

Beyond mere aesthetics, the vibrant hues of fruits, vegetables, and culinary creations evoke sensory experiences that influence perceptions of flavor, freshness, and even nutritional value. This concept highlighted the pivotal role that color can play in the realm of food, serving as a powerful tool to captivate consumers and entice their taste buds.

Ralph Steinman discovered and defined dendritic cells (DCs) in the 1970s [1] and at the time, no one would have expected the diversity of DC lineages to be discovered as well as their contribution to playing out the orchestra that is the adaptive immune response. In the late 20^th century, researchers identified and characterized various DC subtypes, such as conventional DC (cDC), plasmacytoid DC (pDC), and Langerhans cell (LC).

Psoriasis is a systemic inflammatory skin disease associated with significant comorbidities, yet access to effective systemic treatments remains disparate across racial and ethnic groups. Building upon recent findings of disparities in systemic medication prescriptions and hospitalization outcomes among patients with psoriasis, this commentary explores the pharmacologic, toxicologic, and health equity implications of these inequities.