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Mini Review Open Access
Volume 2 | Issue 1 | DOI: https://doi.org/10.46439/nephrology.2.009

Host range of zoonotic hepatitis E viruses

  • 1PathoGuard Consult, 64342 Seeheim-Jugenheim, Germany
+ Affiliations - Affiliations

Corresponding Author

Albrecht Gröner, info@patho-guard.com

Received Date: November 20, 2020

Accepted Date: April 24, 2021

Abstract

Based on a proposed classification, the family Hepeviridae is divided into two genera: Orthohepevirus and Piscihepevirus. The genus Orthohepevirus, divided into seven species, contains the fast majority of HEV strains identified so far: Orthohepevirus A, B, C and D. Within Orthohepevirus A genotype HEV-1 and HEV-2 infect only humans; for genotype HEV-3 and HEV-4 the predominant host species are pig, wild boar, rabbit, deer, mongoose and human. Genotype HEV-5 and HEV-6 infect wild boar and genotype 7 and 8 camel. Orthohepevirus B infect chicken, Orthohepevirus C infect rat and ferrets and Orthohepevirus D infect bat. In this review article epidemiological aspects of HEV due to crossing species barriers based on infectivity studies are assessed.

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