Aging is associated with a progressive increase in the incidence of neurodegenerative diseases, both in laboratory animals and humans. In rats, aging is accompanied by degenerative and/or atrophic processes in the cholinergic system of the forebrain, as well as morphological changes which parallel a reduction in spatial learning capacity. 

Alzheimer's and Parkinson's diseases are two of the most prominent and complex progressive neurological disorders that have a profound global impact [1,2]. These diseases affect millions of individuals worldwide, causing significant morbidity and placing a substantial burden on healthcare systems and society [3,6]. Despite considerable advancements in understanding these disorders over the years, developing effective treatments remains a complex and multifaceted challenge [7,8].

The emergence of new coronaviruses poses a significant global health threat, as witnessed during recent outbreaks. Coronaviruses were first identified in the 1960s, primarily causing mild respiratory illnesses in humans. The introduction of the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002, on the other hand, constituted a watershed moment. The outbreak began in China and swiftly spread to numerous nations, resulting in severe respiratory sickness and a global public health disaster. The SARS-CoV outbreak demonstrated coronaviruses' ability to cause severe illness and inspired substantial study into their origins and transmission patterns.

A logic model was developed as part of an evaluation of a case management program (CMP) for frequent users in a health and social services center in the province of Québec (Canada). Five approaches were used as part of a qualitative multiple case study methodology: analysis of unpublished documents, review of literature on CMPs for frequent users, in-depth interviews, focus groups with stakeholders and participant observations. Collected data were analyzed using thematic analysis and validated by the health and social services center’s partners.

A popular western misconception dating back to at least the time of President John F Kennedy is that one of the Chinese characters in the word “crisis” means opportunity. The manuscript
“Management of anaphylaxis in children undergoing oral food challenges in an adapted COVID-19 field hospital” [1] detailed a highly successful attempt to not only mitigate the effects of the crisis for
elective care brought by the COVID-19 pandemic but to seek to maximize the opportunity by better utilization and redeployment of staff allowing the team to reduce pre-pandemic waiting lists by 57%.