Wolf-Hirschhorn Syndrome (WHS, OMIM 194190) is a rare congenital malformation syndrome caused by a partial deletion of the short arm (p) of chromosome 4. It is characterized by “Greek warrior helmet” facies, central nervous system disorders including seizures and structural defects, and intrauterine growth restriction, among numerous other systemic anomalies.

This commentary relates to Gwilliam, Joyce, and Dimitriou and their longitudinal work on sleep problems in toddlers with Williams syndrome (WS). WS is a rare and sporadic genetic disorder caused by a small deletion of genes on chromosome 7. Individuals with WS experience a range of medical and developmental difficulties and sleep disturbances are highly prevalent. The aim, here, is to address why early identification of sleep problems could be beneficial for children with WS and their families.

Continuing our report on the coexistence of two culture-bound syndromes, namely Koro and Dhat syndrome coexisting with OCD, we will discuss some relevant psychosexual issues in this context. It is pretty interesting to note that how two culture-bound syndromes facilitate sexual symptom formation among vulnerable individuals. India has now become a Koro-prone country, especially after six large-scale epidemics since 1982. Penile shrinking or retraction or contraction is now a potential social cognitive construct in different forms of actual or alleged complaints of sexual dysfunctions.

Complex Regional Pain Syndrome (CRPS) is a challenging condition marked by intense and often long-lasting pain, typically occurring in a limb following an injury. Traditional treatment approaches might not always offer significant pain relief, prompting the investigation of advanced treatments like Spinal Cord Stimulation (SCS).