American Journal of Aging Science and Research

Non-Alcoholic Fatty Liver Disease (NAFLD) is the growing epidemic which is rapidly increasing in USA. Elderly people are the most affected population which suffers from NAFLD. The earliest stage of NAFLD, hepatic steatosis has no evidence of liver injury, but is characterized by an accumulation of triglycerides in hepatocytes. Hepatic steatosis progresses in age-dependent manner to non-alcoholic steatohepatitis (NASH) and cirrhosis. Mechanisms of development of age associated NAFLD are not well understood and approaches to treat this disease are not developed. Recent studies within last three years; however, provided several lines of evidence showing that although hepatic steatosis strongly correlates with development of NAFLD, it might be not a cause of next steps of NAFLD: fibrosis and NASH. Moreover, some reports suggest that hepatic steatosis might play a protective role in development of fibrosis and NASH. Recent studies of NAFLD in animal models showed that the increase of liver proliferation is the first event in high-fat diet-induced NAFLD.

A strong intergenerational divide in voting behaviour has become a frequently reported stylized fact in post-referendum analyses, raising the question of whether myopia of elderly voters is a cause for concern in ageing societies. However, identifying the origins of a generation gap is empirically challenging because age and birth cohort are collinear at any given point in time. Building on a previous study, we summarize how this problem can be overcome. We discuss an unconstrained rank regression approach that allows estimating the causal ageing effect on political attitudes conditional on arbitrary cohort effects in a flexible manner.

Let us talk about a demographic shift that is affecting the modern world. Not only do we observe a rapid population expansion, but also a considerable change in its structure. In the last few decades, the prevalence of low birth rates and higher life expectancy have altered the demographic structure of the population to one that is much older, a phenomenon dramatically changing the shape of the EU age pyramid and making it top-heavy.

Cephalospinal fluid (CSF) dynamics (secretion and absorption) rate is considered a primary disturbance in the CSF dynamics. CSF reabsorption is a key part of ventriculomegaly, and to a lesser extent other anatomical features of CNS such as elasticity, brain water content, glial cell ratio, tissue atrophy, cranial suture status, age, weight, height, and sex.