Abstract
Cardiovascular disease is a major cause of morbidity and mortality in patients with chronic kidney disease (CKD). Such cardiovascular risk is not limited to those with advanced renal disease, as even patients with early stages of renal dysfunction show increased risk of cardiovascular morbidity and mortality. However, there is a remarkable lack of reliable information regarding the threshold of renal function, increasing the risk of long-term outcomes among patients who underwent multivessel coronary revascularization. Moreover, as patients with mildly decreased renal function were not differentiated from those with normal renal function in most clinical trials on coronary revascularization, there are insufficient data on the prognostic impact and comparative outcomes after percutaneous or surgical revascularization for complex or multivessel CAD in patients with early renal dysfunction.
This review aimed to highlight a recent publication that studied the long-term prognostic impact of baseline renal function, especially mildly decreased renal function on the outcomes after multivessel coronary revascularization.
Keywords
Coronary artery disease, Coronary-artery bypass grafting, Glomerular filtration rate, Percutaneous coronary intervention, Renal function