Abstract
A two herbs formula has been successfully used as a cardiovascular supplement (tonic) to maintain a healthy vascular endothelial state in four groups of patients presenting with different symptom manifestations: coronary obstruction; hypertension; menopausal cardiovascular instability; and peripheral arterial disease. In parallel with the four clinical trials carried out separately in over ten years, laboratory platform studies to find out the mechanisms of action of the herbal formula have been carried out. The bioactivity tests demonstrated the general efficacy of the formula as being anti-inflammatory and anti-oxidative; while in addition, specific influences on vascular relaxation, cardiac protection, endothelial stability and blood lipid cholesterol adjustments were demonstrated.
Loss of arterial patency is the chief culprit for different forms of vascular accidents, and surgical interventional therapy could offer an immediate short-termed solution. The impressive relieving maneuvers yet do not take care of the causative factors like endothelial deposits in response to the changing unfavorable microenvironments provocative for inflammatory changes and lose of smooth muscle relaxation.
The herbal formula, after years of clinical applications and laboratory studies has accumulated evidences that it could serve as an effective supplement to maintain cardiovascular health through multiple bioactivities to harmonize the adverse conditions leading to the decline of cardiovascular competency.
Keywords
Cardio-vascular protection, Herbal supplement, Peripheral arterial disease