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Mini Review Open Access
Volume 1 | Issue 1 | DOI: https://doi.org/10.46439/gastro.1.009

A mini-review of the associations between hypertension and risk of gallstone disease

  • 1Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China
  • 2Department of Epidemiology and Health Statistics, School of Public Health, Shenzhen University Health Science Center, Shenzhen, Guangdong 518061, China
  • 3Department of Health Management, Beijing Xiaotangshan Hospital, Beijing 102211, China
  • 4Graduate faculty, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China
  • 5School of Public Health and Management, Chongqing Medical University, Chongqing 400016, China
  • 6Department of Epidemiology and Biostatistics, Key Laboratory of Cancer Prevention and Therapy, Tianjin Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
  • 7Department of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
  • 8Department of Pharmacy, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
  • 9Department of Prevention, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
  • 10Department of Public Health, Jining Medical University, Jining 272067, China
  • 11Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • 12Department of Pharmacy, The People’s Hospital of Kaizhou District, Chongqing 405400, China
  • 13Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu 610041, China
  • #These authors contributed equally
+ Affiliations - Affiliations

Corresponding Author

 Xin Wang, wangxinmarine@126.com

Received Date: November 10, 2022

Accepted Date: November 23, 2022

Abstract

A series of studies suggested that hypertension is significantly associated with the risk of gallstone disease (GSD). However, due to differences in study design, population stratification, sample size, and diagnostic criteria for GSD, the results of each study are inconsistent, limiting the strength and application of these pieces of evidence. We previously conducted a cross-sectional study incorporating over 300,000 population, and the results showed hypertension was significantly associated with the risk of GSD. However, it was a single-center study, and the external generalization of research results is limited to a certain extent. Thus, we conducted another multi-center study and a systematic review and meta-analysis to verify further the relationship between hypertension and the risk of GSD. 

Keywords

Gallstone diseases, Hypertension, Multi-center study, Systematic review and meta-analysis

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