Journal of Clinical Pediatrics and Neonatology

Children who experience abuse and neglect often have behavioral health sequalae which are poorly addressed because services are not evidence-based and partnerships with behavioral health providers lack precise coordination. Partnering for Success provides interprofessional training on EBPs, communication, and data sharing and has now been expanded to address the unique needs of children in treatment foster care.

The one conceptual key to improving newborn healthcare outcomes is thought to be bridging the access gap to care, particularly in sub-Saharan Africa. However, recent studies have reported conflicting results relative to establishing a link between outcomes and access to care intervention programs.

Neonatal cholestasis (NC) is usually a result of hepatobiliary dysfunction and can lead to extensive workup and prolonged stay in the NICU. NC is never physiological but rather a sign of hepatobiliary and/or metabolic disorders, some of which can become fatal if it is not identified and treated in time.

Mother-to-child transmission (MTCT) through breastfeeding remains a major source of pediatric HIV-1 infection worldwide. To characterize plasma HIV-1 subtype C populations from infected mothers during pregnancy that related to subsequent breast milk transmission, an exploratory study was designed to apply next generation sequencing and a custom bioinformatics pipeline for HIV-1 gp41 extending from heptad repeat region 2 (HR2) through the membrane proximal external region (MPER) and the membrane spanning domain (MSD).

We are writing to promote a novel Bayesian dynamic borrowing approach, the empirical profile Bayesian estimation, in the published article "Yaoshi Wu, Jianan Hui, Qiqi Deng. Empirical profile Bayesian estimation for extrapolation of historical adult data to pediatric drug development. Pharmaceutical statistics 2020; 19; 787-802. http://dx.doi.org/10.1002/pst.2031."

It may seem irony that nutrition science historically pertained mostly to undernutrition and deficiency syndromes [1] but nowadays prevention, control and treatment of overnutrition, manifested as overweight and obesity, has become the main task of most nutritionists and related professionals [2]. 

The tongue is a complex muscular organ essential for speech, taste, chewing and swallowing [1]. Tongue injuries range in severity from minor lacerations to complete amputation. The most common location is anterior dorsum as a result of falls, seizures, self-mutilation, electroconvulsive therapy or child abuse [1,2]. 

A 2-month-old girl came to our Radiology Department to perform an abdominal ultrasound. At 38 weeks she was born and she was hospitalized for 3 weeks due to intrauterine growth retardation and hypotonia and the results of the medical study were normal, included cerebral and abdominal ultrasound exception karyotype (47 XX with chromosome marker of unknown origin).

There are many reasons why people may feel hesitant to accept vaccines for their children, with fears about a link between vaccines and autism spectrum disorder (ASD) being one of the most common. In fact, parents of children with ASD are among those most likely to become vaccine hesitant. Vaccine-hesitant parents may delay and/or refuse one or more vaccines for their children, which subsequently places them at increased risk for contracting and spreading vaccine-preventable diseases.

Achieving and maintaining recommended vaccination coverage is a major public health goal [1]. Indeed, rates of childhood vaccine coverage in the U.S. among young children have remained high and stable in recent years [2]. While racial/ethnic disparities in recommended childhood vaccine coverage in the general population have been absent or reduced over time, income disparities have changed at different rates within racial/ethnic groups and in some cases have increased [3].

We are profoundly glad to be engaged in Dr. Klassen’s work of “An international study to develop the EAR-Q patient-reported outcome measure for children and young adults with ear conditions [1]”, our center provided over 40% data for this EAR-Q study. Dr. Klassen [1,2] has already proved the acceptability, reliability and validity of EAR-Q, it can be widespread used for varied ear conditions. 

A 22-day-old male neonate was admitted to the neonatal intensive care unit (NICU) with complaints of abnormal movements, fever, breath holding spells, refusal and bluish discoloration of skin. He was born at term with a birthweight of 2·72 kg to a mother with a history of positive polymerase chain reaction for SARS-Coronavirus-2 (SARS-COV-2) virus (RT-PCR-positive), asymptomatic 2019 novel coronavirus disease (COVID-19) at 32-33 weeks gestation, which did not require any supportive measures.

In a recent issue of the Children and Youth Services Review, I published an article examining systems of support for LGBTQ youth transitioning from foster care to emerging adulthood [1]. The methodology I used to gather this data included in-depth interviewing combined with ecomapping techniques that I modified to identify the strength and structure of LGBTQ youths’ support networks. 

In a follow-up to the 2016 paper “Preweaning iron deficiency increases non-contingent responding during cocaine self-administration in rats”, we briefly discuss relevant new data regarding iron deficiency published through August, 2021. The original work investigated if early iron deficiency would increase later vulnerability for substance use disorder.

Hypoxic-ischemic encephalopathy (HIE) continues to be an important cause of long-term neurologic disability among newborn infants. The estimated incidence ranges from 2-3/1000 live births in developed countries, to as high as 10-20/1000 in developing countries [1]. Affected infants who survive are at a 25% risk for cerebral palsy, epilepsy, and cognitive deficits and may require lifelong medical care.

The pediatric liver cancer hepatoblastoma (HBL) has a complex etiology which is not yet determined. In contrast to adult liver cancer hepatocellular carcinoma (HCC), pediatric HBL has a low rate of genetic mutations suggesting that other mechanisms play a critical role in development of this disease.

Neonatal abstinence syndrome (NAS) represents a serious emotional toll for the families of affected children and represents a significant financial burden for healthcare providers. Historically, patients living in rural regions, such as Appalachia, have limited access to healthcare facilities. 

In the respiratory management of preterm infants of less than 33 weeks gestational age and very low birth weight infants, it is essential to understand changes in chest X-ray and blood gas findings in addition to observing their clinical symptoms.

In 2019, an estimated 2 million babies were stillborn [1] and 2.4 million died within 28 days of life (neonatal deaths) [2]. About 80% of these stillbirth and neonatal deaths occurred in low- and lower-middle- income countries (LMICs) with sub-Saharan Africa region contributing to more than 50% of these deaths [1-3]. 

Congenital Cytomegalovirus (cCMV) infection is the leading cause of non-hereditary sensorineural hearing loss (SNHL) and developmental delay in children with an approximate prevalence rate of 0.7% [1].