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Journal of Pain Research and Management
ISSN: 3067-9427
2025
Volume 1, Issue 1, p1-104
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
The effect of preoperative in-person education on the pain severity of patients undergoing coronary artery bypass graft (CABG) surgery
Roghayeh Sadeghi, Touraj Babaee, Hooman Bakhshandeh, Maziar Naderi
Pain is one of the most common symptoms experienced by patients undergoing coronary artery bypass graft (CABG) surgery. Adequate pain management is critical to the well-being and overall recovery of these patients. This study aimed to evaluate the effect of preoperative in-person pain education on the pain severity experienced by patients undergoing CABG surgery in Rajaie Cardiovascular, Medical and Research Center in Tehran in 2022. In this quasi-experimental study, 72 patients undergoing coronary artery bypass surgery were selected and randomly divided into intervention (n=36) and control (n=36) groups.
J Pain Res Manag, 2025, Volume 1, Issue 1, p1-10 | DOI: 10.46439/Painresearch.1.001
Fibromyalgia, perfectionism, and interpersonal style. Further evidence for a person-centered approach
Frank Maes, Greet Vanaerschot, Els Goossens, Boudewijn Van Houdenhove
Fibromyalgia (FM) is usually considered a ‘medically unexplained’ chronic pain disorder with no known causal treatment. The disorder is also referred to as a ‘functional somatic syndrome’ in which psychological factors are believed to play an important role. According to recent criteria of the American College of Rheumatology (ACR), the main symptom is unexplained widespread pain for at least 3 months; associated symptoms include fatigue, impaired concentration, non-restorative sleep, stimulus intolerance, post-exertional malaise, and various complaints related to neuro-vegetative dysfunction.
J Pain Res Manag, 2025, Volume 1, Issue 1, p11-18 | DOI: 10.46439/Painresearch.1.002
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Alpha 2 adrenoceptors but not GABA participate in electroacupuncture-induced orofacial antinociception at ST36 point in rats
Renato Teixeira Almeida, Giovane Galdino, Andrea Castro Perez, Thiago Roberto Romero, Igor Dimitri Gama Duarte
Orofacial pain represents a significant portion of the complaints from patients seeking treatment at pain management centers worldwide. Although the treatment for orofacial pain is primarily pharmacological, there has been an increase in reports showing significant clinical results from non-pharmacological therapies, including electroacupuncture (EA).
J Pain Res Manag, 2025, Volume 1, Issue 1, p19-27 | DOI: 10.46439/Painresearch.1.003
Exploring AI for pain research management: A deep dive investigative exploration
Zarif Bin Akhtar
Chronic pain still remains a complex healthcare challenge impacting millions of people worldwide, demanding innovative solutions to enhance patient outcomes and alleviate the burden towards healthcare systems. This research investigates the transformative potential of Artificial Intelligence (AI) in chronic pain management, emphasizing its application in personalized diagnostics, predictive modeling, and optimized treatment strategies.
J Pain Res Manag, 2025, Volume 1, Issue 1, p28-42 | DOI: 10.46439/Painresearch.1.004
A review of waveform and paradigm variations of spinal cord stimulation for the treatment of complex regional pain syndrome
Vahid Mohabbatii (MD, FRACGP, FFPMANZCA, FAChPM, AFRACMA), Parsa Mohabbati, Mohammadkazem Papan Ph.D.
Complex Regional Pain Syndrome (CRPS) is a challenging condition marked by intense and often long-lasting pain, typically occurring in a limb following an injury. Traditional treatment approaches might not always offer significant pain relief, prompting the investigation of advanced treatments like Spinal Cord Stimulation (SCS).
J Pain Res Manag, 2025, Volume 1, Issue 1, p43-56 | DOI: 10.46439/Painresearch.1.005
Balancing autonomic nervous system activity through hypnosis clinical implications for pain therapy
Giuseppe De Benedittis
Hypnosis, a clinically valuable therapeutic modality, is increasingly recognized for its efficacy in treating a spectrum of psychological and somatic disorders, including pain. Its influence extends beyond central nervous system processes to encompass the autonomic nervous system (ANS), thereby affecting peripheral physiological responses.
J Pain Res Manag, 2025, Volume 1, Issue 1, p57-61 | DOI: 10.46439/Painresearch.1.006
Voices in the night: Sleep paralysis & The intersection of brain, trauma, traditions
Zarif Bin Akhtar
Sleep Paralysis (SP) is a complex and multifaceted phenomenon situated at the intersection of neurobiology, psychiatry, genetics, and cultural belief systems. This study offers a comprehensive investigation into SP, integrating findings from neurophysiological, psychological, and sociocultural domains. Neurobiological evidence highlights disruptions during the rapid eye movement (REM) sleep cycle—specifically the persistence of REM atonia into wakefulness—as a core mechanism underlying SP, often accompanied by vivid hallucinations and sensory distortions.
J Pain Res Manag, 2025, Volume 1, Issue 1, p62-74 | DOI: 10.46439/Painresearch.1.007
Evaluation of the role of potassium and chloride channels in peripheral antinociception induced by epoxyeicosatrienoic acids (EETs) in mice
Flávia Cristina de Sousa Fonseca, Walace Cássio Pinto Barra, Andrea Castro Perez, Thiago Roberto Romero, Igor Dimitri Gama Duarte
The hyperpolarization of neuronal membranes through the activation of potassium and chloride channels is a significant mechanism involved in the antinociceptive effects of various drugs. Thus, in this study, we aimed to determine whether potassium or chloride channels mediate the peripheral antinociceptive effects of epoxyeicosatrienoic acids (EETs). The mechanical paw pressure test was utilized as an algesimetric method.
J Pain Res Manag, 2025, Volume 1, Issue 1, p75-82 | DOI: 10.46439/Painresearch.1.008
Prevalence and management of pain disorders among patients of different stages of life at cape coast teaching hospital, Ghana
Ernest Obese, Douglas Arthur, Oluwayemisi Esther Ekor, Ivan Eduku Mozu, Ransford Kumah, James Kojo Prah, Jerry Kwesi Kumah Eshun, Kwame Ofori, Mawuli Kotope Gyakobo, Elvis Ofori Ameyaw
Pain represents a significant global health issue with serious consequences for both individual well-being and societal functioning. The International Association for the Study of Pain (IASP) characterizes pain as an "unpleasant sensory and emotional experience linked to actual or potential tissue damage".
J Pain Res Manag, 2025, Volume 1, Issue 1, p83-93 | DOI: 10.46439/Painresearch.1.009
Trauma and treatment: Pain management in Puerto Rican elders visiting the emergency department
Francisco Lasanta Gorbea, M.D., Itzamar Pastrana, M.D., Abner Limardo-Irizarry, M.D., Tania Vega, Laura Lebron, Edgardo Martínez- Berdecia, M.D., Javier Torres-Acevedo, M.D., Miguel Agrait-González, M.D., Fabian Ramírez-Rivera, MPH
As of 2024, adults aged 65 and older account for over 10% of the global population, nearly double the 1974 figure and still rising. In the island of Puerto Rico, the proportion of older adults has increased greatly, from approximately 13% of the population being over 65 years in 2014, to 24.6% of the population in 2024.
J Pain Res Manag, 2025, Volume 1, Issue 1, p94-99 | DOI: 10.46439/Painresearch.1.010
Diagnosis in the mist: Reflections on a misdiagnosed case of invasive pulmonary aspergillosis
Yongfen Zeng, Zhuqiang Cheng
This paper analyzes a misdiagnosed case of invasive pulmonary aspergillosis (IPA) presenting with left upper limb pain as an atypical symptom, exploring cognitive blind spots in clinical diagnosis, limitations in imaging and laboratory examinations, and therapeutic challenges. It emphasizes the importance of multidisciplinary collaboration in complex cases.
J Pain Res Manag, 2025, Volume 1, Issue 1, p100-102
Beyond prayer: Expanding the understanding of quality of life in Tanzanian palliative care
Sonia Nada
The recently published study “Religious practices and quality of life in palliative care: insights from Tanzania” has brought to the forefront the indispensable role of spiritual practices in supporting patients with advanced cancer. The overwhelming demand for prayer and faith-based engagement demonstrates how religion provides meaning, resilience, and comfort in the face of terminal illness.
J Pain Res Manag, 2025, Volume 1, Issue 1, p103-104
Recommended Articles
Fibromyalgia, perfectionism, and interpersonal style. Further evidence for a person-centered approach
Fibromyalgia (FM) is usually considered a ‘medically unexplained’ chronic pain disorder with no known causal treatment. The disorder is also referred to as a ‘functional somatic syndrome’ in which psychological factors are believed to play an important role. According to recent criteria of the American College of Rheumatology (ACR), the main symptom is unexplained widespread pain for at least 3 months; associated symptoms include fatigue, impaired concentration, non-restorative sleep, stimulus intolerance, post-exertional malaise, and various complaints related to neuro-vegetative dysfunction.
The effect of preoperative in-person education on the pain severity of patients undergoing coronary artery bypass graft (CABG) surgery
Pain is one of the most common symptoms experienced by patients undergoing coronary artery bypass graft (CABG) surgery. Adequate pain management is critical to the well-being and overall recovery of these patients. This study aimed to evaluate the effect of preoperative in-person pain education on the pain severity experienced by patients undergoing CABG surgery in Rajaie Cardiovascular, Medical and Research Center in Tehran in 2022. In this quasi-experimental study, 72 patients undergoing coronary artery bypass surgery were selected and randomly divided into intervention (n=36) and control (n=36) groups.
Prevalence and management of pain disorders among patients of different stages of life at cape coast teaching hospital, Ghana
Pain represents a significant global health issue with serious consequences for both individual well-being and societal functioning. The International Association for the Study of Pain (IASP) characterizes pain as an "unpleasant sensory and emotional experience linked to actual or potential tissue damage".
Alpha 2 adrenoceptors but not GABA participate in electroacupuncture-induced orofacial antinociception at ST36 point in rats
Orofacial pain represents a significant portion of the complaints from patients seeking treatment at pain management centers worldwide. Although the treatment for orofacial pain is primarily pharmacological, there has been an increase in reports showing significant clinical results from non-pharmacological therapies, including electroacupuncture (EA).
Trauma and treatment: Pain management in Puerto Rican elders visiting the emergency department
As of 2024, adults aged 65 and older account for over 10% of the global population, nearly double the 1974 figure and still rising. In the island of Puerto Rico, the proportion of older adults has increased greatly, from approximately 13% of the population being over 65 years in 2014, to 24.6% of the population in 2024.
Exploring AI for pain research management: A deep dive investigative exploration
Chronic pain still remains a complex healthcare challenge impacting millions of people worldwide, demanding innovative solutions to enhance patient outcomes and alleviate the burden towards healthcare systems. This research investigates the transformative potential of Artificial Intelligence (AI) in chronic pain management, emphasizing its application in personalized diagnostics, predictive modeling, and optimized treatment strategies.
A review of waveform and paradigm variations of spinal cord stimulation for the treatment of complex regional pain syndrome
Complex Regional Pain Syndrome (CRPS) is a challenging condition marked by intense and often long-lasting pain, typically occurring in a limb following an injury. Traditional treatment approaches might not always offer significant pain relief, prompting the investigation of advanced treatments like Spinal Cord Stimulation (SCS).
Balancing autonomic nervous system activity through hypnosis clinical implications for pain therapy
Hypnosis, a clinically valuable therapeutic modality, is increasingly recognized for its efficacy in treating a spectrum of psychological and somatic disorders, including pain. Its influence extends beyond central nervous system processes to encompass the autonomic nervous system (ANS), thereby affecting peripheral physiological responses.
Voices in the night: Sleep paralysis & The intersection of brain, trauma, traditions
Sleep Paralysis (SP) is a complex and multifaceted phenomenon situated at the intersection of neurobiology, psychiatry, genetics, and cultural belief systems. This study offers a comprehensive investigation into SP, integrating findings from neurophysiological, psychological, and sociocultural domains. Neurobiological evidence highlights disruptions during the rapid eye movement (REM) sleep cycle—specifically the persistence of REM atonia into wakefulness—as a core mechanism underlying SP, often accompanied by vivid hallucinations and sensory distortions.
Evaluation of the role of potassium and chloride channels in peripheral antinociception induced by epoxyeicosatrienoic acids (EETs) in mice
The hyperpolarization of neuronal membranes through the activation of potassium and chloride channels is a significant mechanism involved in the antinociceptive effects of various drugs. Thus, in this study, we aimed to determine whether potassium or chloride channels mediate the peripheral antinociceptive effects of epoxyeicosatrienoic acids (EETs). The mechanical paw pressure test was utilized as an algesimetric method.
Diagnosis in the mist: Reflections on a misdiagnosed case of invasive pulmonary aspergillosis
This paper analyzes a misdiagnosed case of invasive pulmonary aspergillosis (IPA) presenting with left upper limb pain as an atypical symptom, exploring cognitive blind spots in clinical diagnosis, limitations in imaging and laboratory examinations, and therapeutic challenges. It emphasizes the importance of multidisciplinary collaboration in complex cases.
Beyond prayer: Expanding the understanding of quality of life in Tanzanian palliative care
The recently published study “Religious practices and quality of life in palliative care: insights from Tanzania” has brought to the forefront the indispensable role of spiritual practices in supporting patients with advanced cancer. The overwhelming demand for prayer and faith-based engagement demonstrates how religion provides meaning, resilience, and comfort in the face of terminal illness.